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Table 'scialert_sa.1819-155X-ab' doesn't exist
Current Research in Cardiovascular Pharmacology
  Year: 2017 | Volume: 6 | Issue: 1 | Page No.: 17-21
DOI: 10.3923/crcpaj.2017.17.21
 
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Pharmacological Effects of Atorvastatin and Cholesterol and Blood Pressure
P. Papitha, P. Sujeetha, K.S. Balajee, T. Sangeetha and A. Vijaya Anand

Abstract:
Cholesterol is a precursor for bile acids and steroid hormones. High concentration of cholesterol in the blood leads to hypercholesterolemia and blood pressure, which may possibly associate with atherosclerotic vascular disease and increased frequency of vascular events. Decreasing of Low Density Lipoprotein (LDL) cholesterol is an important target for the treatment of cardiovascular disease (CVD). Atorvastatin is a 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA) inhibitors are the most effective classes of drugs for reducing serum LDL cholesterol level. This review focuses on the pharmacological effects of atorvastatin in lowering cholesterol and control of blood pressure.
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