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Chemical Profiling, Phytochemical Constituents and in vitro Antioxidant Activities of Ethanol Leaf Extract of Talinum triangulare |
Johnson O. Oladele ,
Boyede D. Olowookere ,
Mutiat O. Bamigboye,
Oyedotun M. Oyeleke ,
Kehinde E. Alabi,
Opeyemi O. Oladele and Israel O. Oyewole |
Abstract:
Background and Objective: Reports from robust scientific and clinical studies have proven the efficacies of phytochemicals, antioxidants and vitamins in the amelioration and treatment of complications arising from excessive oxidative stress. This study was designed to carry out the phytochemistry of the natural compounds present in ethanol leaf extract of Talinum triangulare and to assess the in vitro antioxidant activities of the extract. Materials and Methods: Chemical composition with secondary metabolites profiling in the extract were carried out using standard procedure and Fourier-Transform Infrared Spectroscopy (FTIR) spectrophotometry and in vitro, antioxidant activities of the extract were assessed by evaluating hydrogen peroxide, hydroxyl radical, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activities and ferric reducing antioxidant power methods. Results: The phytochemical analysis of the extract showed the presence of coumarins, terpenoids, flavonoids, alkaloids, phenols, saponins, quinones, vitamin C, glycosides and betacyanin. Further, the FTIR analysis showed the presence of aliphatic bromo, aromatic fluoro, aromatic primary amine, trimethyl, methyl alkenyl, methylene, dimeric OH, alkanes, alkenes and aromatic ring groups. In vitro, antioxidant assays results also reveal that the extract free radical scavenging abilities are significantly high when compared with standard antioxidants used (gallic and ascorbic acids). Conclusion: Taken together, the results from this study suggest the extract as a source of natural antioxidants that could have considerable therapeutic relevance in preventing and inhibiting the progression of diseases associated with oxidative stress.
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Johnson O. Oladele, Boyede D. Olowookere, Mutiat O. Bamigboye, Oyedotun M. Oyeleke, Kehinde E. Alabi, Opeyemi O. Oladele and Israel O. Oyewole, 2021. Chemical Profiling, Phytochemical Constituents and in vitro Antioxidant Activities of Ethanol Leaf Extract of Talinum triangulare. Current Research in Chemistry, 13: 26-34. DOI: 10.3923/crc.2021.26.34 URL: https://scialert.net/abstract/?doi=crc.2021.26.34
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