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Current Research in Chemistry
  Year: 2012 | Volume: 4 | Issue: 3 | Page No.: 68-75
DOI: 10.3923/crc.2012.68.75
 
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Efficient p-Amino Benzoic Acid Catalyzed Eco-friendly Synthesis of 1,5-benzodiazepines among Various Amino Acids under Solvent Free Conditions

Akshdeep Sandhar, Deo Nandan Prasad, Abhinav Kapoor and Rajesh K. Singh

Abstract:
p-Amino benzoic acid was found to be the versatile acidic amino acid catalyst among various amino acids tested for the preparation of 1,5-benzodiazepines derivatives from a wide range of substituted o-phenylenediamines and ketones. The corresponding products were obtained in good isolated yields (85-92%) at room temperature under solvent free conditions. Simple and effective method, use of non-hazardous catalyst and good to excellent yields are the important features of this method.
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How to cite this article:

Akshdeep Sandhar, Deo Nandan Prasad, Abhinav Kapoor and Rajesh K. Singh, 2012. Efficient p-Amino Benzoic Acid Catalyzed Eco-friendly Synthesis of 1,5-benzodiazepines among Various Amino Acids under Solvent Free Conditions. Current Research in Chemistry, 4: 68-75.

DOI: 10.3923/crc.2012.68.75

URL: https://scialert.net/abstract/?doi=crc.2012.68.75

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