Research Article

In vitro Antibacterial Properties of Total Alkaloids Extract from Mitragyna Inermis (Willd.) O. Kuntze, a West African Traditional Medicinal Plant

C. Zongo, Etienne-Francois O. Akomo, A. Savadogo, Louis Clement Obame, Jean Koudou and Alfred S. Traore

The antimicrobial activity of the total alkaloids from the leaves of Mitragyna inermis (Willd.) O. Kuntze (Rubiaceae) From Burkina Faso was evaluated using disc diffusion essay and broth microdilution assay. The extract was used against ten (10) reference bacterial strains and three (3) clinical isolates including Gram(+) and Gram(-) strains. The alkaloids showed moderate activity against mcroorganisms tested. The highest Diameter of Inhibition Zone (DIZ) was obtained with S. aureus ATCC9244 (23 ± 1 mm). The lowest Minimum Inhibitory Concentration (MIC) obtained was 0.625 mg mL^-1 recorded with three (3) Gram(+) bacteria (S. aureus ATCC 25293, S. aureus (clinical isolate) and S. carmorum LMG 13567) and one Gram(-) strain (P. mirabilis CIP104588. Results showed that Gram(+) bacteria are more sensitive to alkaloids from M. inermis than Gram(-) bacteria. This study confirmed the use of the plant in traditional medicine against some infectious diseases.

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How to cite this article

C. Zongo, Etienne-Francois O. Akomo, A. Savadogo, Louis Clement Obame, Jean Koudou and Alfred S. Traore, 2009. In vitro Antibacterial Properties of Total Alkaloids Extract from Mitragyna Inermis (Willd.) O. Kuntze, a West African Traditional Medicinal Plant. Asian Journal of Plant Sciences, 8: 172-177.

DOI: 10.3923/ajps.2009.172.177

URL: https://scialert.net/abstract/?doi=ajps.2009.172.177

Comments

ahmad shafiei darabi Reply

18 March, 2009

Dear
I am ahmad shafiei
I graduated from shahid beheshti university, Iran
I work on galbanum and have a paper about it.
The title of paper is "The comparison of galbanum (Ferula gummosa Boiss) from five regions of Iran"
Pleas send your address or email
Thanks

zongo cheikna

10 June, 2010

Thank you for you interest for my work. You can make contact with me for scientic exchanges and over.
Best regards!

saeed aria Reply

01 April, 2009

hello i am horticulture engineerig student in tehran!
i"d look like
your aricle was good

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Authors

C. Zongo

Etienne-Francois O. Akomo

A. Savadogo

Louis Clement Obame

Jean Koudou

Alfred S. Traore

Keywords