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Asian Journal of Plant Sciences
  Year: 2003 | Volume: 2 | Issue: 17 | Page No.: 1162-1165
DOI: 10.3923/ajps.2003.1162.1165
 
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An Antimicrobial Terpenoid from Caesalpinia pulcherrima Swartz.: Its Characterization, Antimicrobial and Cytotoxic Activities

A.K.M. Nasimul Islam, M. Abbas Ali , Abu Sayeed , Syed M. Abdus Salam , Anwarul Islam , Motiur Rahman , G.R.M. Astaq Mohal Khan and Seatara Khatun

Abstract:
A terpenoid, 3-oxo-(20S, 24S)-epoxydammarane-19,25-diacetate (CP-1) isolated from the chloroform extract of barks of Caesalpinia pulcherrima was characterized on the basis of spectral data coupled with chemical evidence. The compound showed significant antibacterial activity against a number of pathogenic bacteria and prominent antifungal activity against a few fungi. The minimum inhibitory concentration (MIC) values against Bacillus cereus and Shigella dysenteriae were 16 μg ml-1 and 32 μg ml-1 respectively. The compound was found cytotoxic against brine shrimp and LC50 value was 8.41 μg ml-1. These findings suggested for further clinical trial.
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How to cite this article:

A.K.M. Nasimul Islam, M. Abbas Ali , Abu Sayeed , Syed M. Abdus Salam , Anwarul Islam , Motiur Rahman , G.R.M. Astaq Mohal Khan and Seatara Khatun , 2003. An Antimicrobial Terpenoid from Caesalpinia pulcherrima Swartz.: Its Characterization, Antimicrobial and Cytotoxic Activities. Asian Journal of Plant Sciences, 2: 1162-1165.

DOI: 10.3923/ajps.2003.1162.1165

URL: https://scialert.net/abstract/?doi=ajps.2003.1162.1165

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