Abstract:
The phytochemical screening and antioxidant properties of the leaves of Ormocarpum
cochinchinense L. were studied after extraction of various compounds in
it using different solvents. The different solvents used for extraction was,
dimethyl sulfoxiamide (DMSO), Ethyl Acetate (EtoAc), ethanol (EtOH), methanol
(MeOH) and chloroform (CHCl3). Antioxidant potential was evaluated
by using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity.
The DMSO, EtoAc, EtOH, MeOH, CHCl3, extracts showed significant (p<0.001)
antioxidant potentiality in a dose-dependent manner. Its IC50 values
(13.05±0.39; 14.08±0.42; 15.02±0.45; 16.12±0.48;
14.88±0.44 μg mL-1) were compared to the IC50
value of the reference standard ascorbic acid (06.10±0.18; 07.18±0.21;
08.15±0.24; 09.10±0.27; 08.18±0.23 μg mL-1)
which suggested that the Ormocarpum cochinchinense is a potent antioxidant.
The phytochemical evaluation indicated the presence of chemical constituents
including flavonoids, alkaloids, steroids, terpenoids, saponins, gums, tannins,
resins, coumarins, glycosides, carbohydrates. This study also shows that the
different solvent extract of leaves of O. cochinchinense has bioactivity.
Further the compound needs to be isolated to confirm the activities of the individual
compounds.
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