Evaluation of Root Extracts of Asparagus racemosus for Antibacterial Activity

Research Article

**Evaluation of Root Extracts of Asparagus racemosus for Antibacterial Activity**

Himanshu Aggarwal, Gyanprakash, Alka Rao and Vinod Chhokar

The root extract of Asparagus racemosus was studied in vitro against five strains of bacteria by using agar well/disc-diffusion method and growth inhibition in liquid culture. Among the three different extraction methods namely, cold maceration method, soxhlet extraction and reflux extraction that were employed for the extraction of bioactive components from the roots of the A. racemosus, the methanolic extract prepared by reflux extraction was found to have the maximum antibacterial activity against Escherichia coli DH5α and Pseudomonas aeruginosa (MTCC1688). The MIC value of methanolic A. racemosus Root Extract (ARE) as determined by agar disc diffusion assay was found considerably significant for a crude extract at 0.5 mg mL^-1 against P. aeruginosa (MTCC1688) and as low as 0.25 mg mL^-1 in case of E. coli DH5α in comparison with the synthetic antibiotic ampicillin.

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Himanshu Aggarwal, Gyanprakash, Alka Rao and Vinod Chhokar, 2013. Evaluation of Root Extracts of Asparagus racemosus for Antibacterial Activity. American Journal of Drug Discovery and Development, 3: 113-119.

DOI: 10.3923/ajdd.2013.113.119

URL: https://scialert.net/abstract/?doi=ajdd.2013.113.119

American Journal of Drug Discovery and Development

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Authors

Himanshu Aggarwal

Gyanprakash

Alka Rao

Vinod Chhokar

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Research Article

**Evaluation of Root Extracts of Asparagus racemosus for Antibacterial Activity**

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