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Asian Journal of Clinical Nutrition
  Year: 2014 | Volume: 6 | Issue: 3 | Page No.: 75-80
DOI: 10.3923/ajcn.2014.75.80
Comparative Study on the Harmful Effect of Salt Ingestion and its Dietary Restriction in Wistar Rats
O.A. Iyamu

Abstract:
In addition to hypertension, salt inclusion in the diet especially after cooking, has been link with several cardiovascular system diseases and metabolic syndrome. This study was therefore, undertaken to investigate the effect of salt inclusion in the diet and its restriction (reversal effect) on body weight, pulse rate, blood glucose and lipid profile of Wistar rat. The study was conducted on 18 Wistar rats grouped into A, B and C. Group A served as the control and received control diet (100 g feed) for six weeks. On the other hand, group B received test diet (92 g feed+8 g salt) for six weeks. However, group C (reversal effect group) received test diet for the 1st three weeks and then was on control diet for the next three weeks. Prior to, three weeks into and at the end of the study, body weight, pulse rate and blood glucose were determined using standard procedures while lipid profile was determined at the end of the study. The results showed that salt has a reducing effect on mean body weight and good lipid-cholesterol but an increasing effect on pulse rate, blood glucose and bad lipid-cholesterol. Based on these findings, dietary salt has a harmful effect on body weight, blood pressure and glucose level.
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How to cite this article:

O.A. Iyamu , 2014. Comparative Study on the Harmful Effect of Salt Ingestion and its Dietary Restriction in Wistar Rats. Asian Journal of Clinical Nutrition, 6: 75-80.

DOI: 10.3923/ajcn.2014.75.80

URL: https://scialert.net/abstract/?doi=ajcn.2014.75.80

 
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