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Asian Journal of Biological Sciences
  Year: 2019 | Volume: 12 | Issue: 2 | Page No.: 251-257
DOI: 10.3923/ajbs.2019.251.257
Antioxidant Phytochemical Screening and Antimicrobial Activity of Ficus exasperata Against Pathogens in Nigeria
Parvaze Ahmad Wani , Olaoye Felix Adesina, Shazia Wahid, Oladapo Rahman Salami and Neelofar Jan

Abstract:
Background and Objective: Development of microbial resistance to drugs has led scientists to study the role of natural substances such as medicinal plants with antimicrobial and antioxidant activity compared to synthetic drugs. Aim of present study was to evaluate antimicrobial and antioxidant activities of Ficus exasperata leaves against selected human pathogens and also screen medicinal plant for phytochemical activity in comparison to the synthetic drugs. Materials and Methods: Ficus exasperata was screened for phytochemicals by standard methods, it was also observed for their antimicrobial activity by agar well diffusion methods. Antioxidant activities were assessed on the basis of the scavenging effect of the 2, 2-dipheny-1-pircryl hydrazyl (DDPH) free radicals activity. Results: Phytochemical screening showed presence of steroids, tannins, saponins, anthocyanins, phenols, anthraquinones, flavonoids, terpenoids and alkaloids. Highest concentrations of extracts resulted in highest antimicrobial activity. Ethyl acetate extracts showed highest antimicrobial activity against pathogens which was followed by methanolic extract. Lowest minimum inhibitory concentration was also shown by ethyl acetate, followed by methanol. As concentration of plant extract increased, antioxidant activity also increased. Ethyl acetate was able to show highest activity of antioxidants compared to other solvents. Conclusion: Based on broad spectrum activity of F. exasperata extracts as revealed by this research supports its usage as natural antimicrobial and antioxidant compared to the synthetic drugs.
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How to cite this article:

Parvaze Ahmad Wani, Olaoye Felix Adesina, Shazia Wahid, Oladapo Rahman Salami and Neelofar Jan, 2019. Antioxidant Phytochemical Screening and Antimicrobial Activity of Ficus exasperata Against Pathogens in Nigeria. Asian Journal of Biological Sciences, 12: 251-257.

DOI: 10.3923/ajbs.2019.251.257

URL: https://scialert.net/abstract/?doi=ajbs.2019.251.257

 
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