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Asian Journal of Biological Sciences

Year: 2008 | Volume: 1 | Issue: 2 | Page No.: 84-89
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Authors

E.S. Orhue

M. Idu

J.E. Ataman

L.E. Ebite

Keywords

Research Article

Haematological and Histopathological Studies of Jatropha tanjorensis (J.L. Ellis and Soroja) Leaves in Rabbits

E.S. Orhue, M. Idu, J.E. Ataman and L.E. Ebite
This study investigated the possible toxicity of consumption of the leaf by determining a variety of serum biochemical parameters in liver and renal function tests, haematological and physical parameters. A 5 week repeated dose toxicity of Jatropha tanjorensis leave powder was carried out in rabbits. Forty animals, male and female, were administered feed mash plus ground J. tanjorensis leaf powder in graded concentrations of 0, 5, 10 and 25%. All rabbits survived at the end of the study and results showed no significant alteration in average body weight in the treatment groups when compared with the control group. The haemoglobin, hematocrit, platelets and platelet cell distribution width in the female group, showed significant increase between the control and the treated groups. This is an indication of an improved bone marrow function. No severe histopathologic indicator was recorded.
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E.S. Orhue, M. Idu, J.E. Ataman and L.E. Ebite, 2008. Haematological and Histopathological Studies of Jatropha tanjorensis (J.L. Ellis and Soroja) Leaves in Rabbits. Asian Journal of Biological Sciences, 1: 84-89.

URL: https://scialert.net/abstract/?doi=ajbs.2008.84.89

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