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American Journal of Biochemistry and Molecular Biology
  Year: 2013 | Volume: 3 | Issue: 1 | Page No.: 151-158
DOI: 10.3923/ajbmb.2013.151.158
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Antidiabetic Effects of Camel Milk in Streptozotocin-induced Diabetic Rats

Amjad Ali Khan, Mohammad A. Alzohairy and Abdelmarouf H. Mohieldein

This study was conducted to analyse the possible antidiabetic effects of camel milk in streptozotocin (STZ)-induced diabetic rats by assaying liver and kidney clinical function parameters. Administration of streptozotocin (55 mg kg-1 b.wt.) to the experimental groups of rats resulted in marked detectable changes. The rats were fed daily with fresh camel milk by feeding bottles for 30 days. The effects of camel milk on blood glucose, serum proteins, urea, uric acid, creatinine, lipid profile and the activities of diagnostic marker enzymes of liver function and Alkaline Phosphatase (ALP) were examined in the plasma/serum of control and experimental groups of rats. Camel milk feeding to diabetic rats significantly reduces the levels of blood glucose, urea, uric acid and creatinine and increases the activities of albumin, albumin/globulin ratio and restores all liver function marker enzymes and lipid profile to near control levels. The present study shows that feeding of camel milk to diabetic rats has antihyperglycemic effects and consequently may alleviate liver and renal damage associated with streptozotocin-induced diabetic rats.
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  •    Inhibitory Activity of Naturally Occurring Compounds Towards Rat Intestinal α-glucosidase using p-nitrophenyl-α-d-glucopyranoside (PNP-G) as a Substrate
  •    Chemical Composition and Antioxidant Activity of Dates and Dates-Camel-Milk Mixtures as a Protective Meal against Lipid Peroxidation in Rats
  •    Study of the Effect of Processing on the Chemical Quality of Soft Unripened Cheese Made from Camel Milk
  •    Changes in Amino Acids Profile of Camel Milk Protein During the Early Lactation
  •    Hepatoprotective Effects of Camel Milk against CCl4-induced Hepatotoxicity in Rats
  •    Changes in Chemical Composition of Camel’s Raw Milk During Storage
How to cite this article:

Amjad Ali Khan, Mohammad A. Alzohairy and Abdelmarouf H. Mohieldein, 2013. Antidiabetic Effects of Camel Milk in Streptozotocin-induced Diabetic Rats. American Journal of Biochemistry and Molecular Biology, 3: 151-158.

DOI: 10.3923/ajbmb.2013.151.158






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