Thiol (-SH) groups are the major intracellular and extracellular
reducing agents. This study estimates such thiol groups in alcohol abusers.
Serum total thiols and liver function test parameters were estimated by
spectrophotometric methods in alcohol abusers on admission (group I) and
thirty days after alcohol abstinence along with life style modification
(group II) and in non-alcoholic healthy controls. Serum amino transaminases,
gamma glutamyl transpeptidase levels were increased and total thiols,
total proteins and albumin levels were decreased in group I cases compared
to group II cases and controls. Total thiols status improved significantly
along with tranasaminases and transapeptidase with thirty days of alcohol
abstinence and life style modification. In conclusion, total thiol status
is decreased in alcohol abusers and abstinence of alcohol along with life
style modification improves thiol antioxidant status and liver function. PDFFulltextXMLReferencesCitation
How to cite this article
Mungli Prakash, Jeevan K. Shetty, Sudeshna Tripathy, Manish Verma, Saddinamane Vasudev and Panambur V. Bhandary, 2008. Serum Total Thiol Status in Alcohol Abusers . Asian Journal of Biochemistry, 3: 48-51.