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Asian Journal of Biochemistry
  Year: 2007 | Volume: 2 | Issue: 1 | Page No.: 73-78
DOI: 10.3923/ajb.2007.73.78
Clinical Effect of Haemodialysis on Plasma Lipid Peroxidation and Cardiac Troponin I in Gorgan (South East of Caspian Sea)
Abdoljalal Marjani, Hamidreza Joshaghani and Golamreza vaghari

Abstract:
The aim of this study with the discriminative information was to evaluate the effect of haemodialysis on plasma lipid peroxidation and Cardiac Troponin I before and after the dialysis process. Twenty two patients with Chronic Renal Failure (CRF) disease who were haemodialyzed at 5th Azar hospital of Gorgan Dialysis Center were recruited for this study (2005). Plasma malondialdehyde was increased significantly in the postdialysis group when compared with predialysis. Plasma levels of Cardiac Troponin I in 12 haemodialyzed patients were significantly increased in the postdialysis group when compared with predialysis, whereas plasma level of Cardiac troponin I in 10 haemodialyzed patients showed less than 0.1 μg L-1 which is in normal range. The observation of meaningful increasing level of plasma lipid peroxidation and Cardiac Troponin I in the haemodialyzed patients after the process of dialysis, maybe related with the patient uremia, dialysis membrane and the dialysis process (may increase lipid peroxidation during the dialysis process). These states of affairs may play an important role in progress of cardiovascular abnormality in haemodialyzed patients. Due to this conditions a review of haemodialysis membrane, the techniques used in the dialysis, the consumption of various oral antioxidant, the elimination of active oxygens from the dialysis surrounding are among the measures which can prevent sudden cardiovascular abnormality in the haemodialysis patients and ultimately these important factors up- grade the patients quality of life and prevent sudden silent myocardial infarction.
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How to cite this article:

Abdoljalal Marjani, Hamidreza Joshaghani and Golamreza vaghari, 2007. Clinical Effect of Haemodialysis on Plasma Lipid Peroxidation and Cardiac Troponin I in Gorgan (South East of Caspian Sea). Asian Journal of Biochemistry, 2: 73-78.

DOI: 10.3923/ajb.2007.73.78

URL: https://scialert.net/abstract/?doi=ajb.2007.73.78

 
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