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Asian Journal of Biochemistry
  Year: 2007 | Volume: 2 | Issue: 6 | Page No.: 421-426
DOI: 10.3923/ajb.2007.421.426
Antiproliferative, Antioxidant and Apoptosis Effects of Zingiber officinale and 6-Gingerol on HepG2 Cells
Harliansyah , Noor Azian Murad , Wan Zurinah Wan Ngah and Yasmin Anum Mohd Yusof

Abstract:
The present study was designed to compare the antioxidant, antiproliferative and apoptosis effects of ethanolic extract of ginger (Zingiber officinale) with its phenolic component (6)-Gingerol on human hepatoma cell line (HepG2). We found that cytotoxic and antiproliferative effect of ginger extract and (6)-Gingerol could be associated with induction of apoptosis. Both ginger extract and (6)-Gingerol also showed remarkable antioxidant activities in comparison with ascorbic acid and N-acetyl-L-cysteine.
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How to cite this article:

Harliansyah , Noor Azian Murad , Wan Zurinah Wan Ngah and Yasmin Anum Mohd Yusof , 2007. Antiproliferative, Antioxidant and Apoptosis Effects of Zingiber officinale and 6-Gingerol on HepG2 Cells. Asian Journal of Biochemistry, 2: 421-426.

DOI: 10.3923/ajb.2007.421.426

URL: https://scialert.net/abstract/?doi=ajb.2007.421.426

 
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