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Asian Journal of Animal and Veterinary Advances
  Year: 2016 | Volume: 11 | Issue: 1 | Page No.: 73-78
DOI: 10.3923/ajava.2016.73.78
 
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Clinical and Pathological Changes in Sheep During a Monensin Toxicity Outbreak in Brasilia, Brazil

Lorena Ferreira Silva, Edson de Figueiredo Gaudencio Barbosa, Ernane de Paiva Ferreira Novaes, Jose Renato Junqueira Borges, Eduardo Mauricio Mendes de Lima and Marcio Botelho de Castro

Abstract:
A monensin poisoning outbreak resulting from a failure in the feed formulation was investigated in a sheep herd in Brasilia, Brazil. Forty sheep died, with a morbidity rate of 33.33% and mortality rate of 100%. Poisoned animals showed attitude, postural, mucosal and cardio-respiratory changes, as well as neutrophilia, lymphopenia and high serum aspartate aminotransferase (AST) and creatine phosphokinase (CPK) levels. At necropsy, the main lesions observed were pale and whitish areas on one or more skeletal muscle groups, in addition to myocardium. Degenerative-necrotic, circulatory and inflammatory changes, fibroplasia and regeneration of muscle fibers were the main histopathological alterations in sheep spontaneously poisoned by monensin. The frequency of skeletal muscle group and myocardium lesions was determined. Striated skeletal muscle groups of monensin-poisoned animals showed degenerative necrotic lesions that were more frequent and intense compared to the myocardium. The detailed characterization of the changes and lesions in sheep intoxicated by monensin may contribute to the diagnosis of toxicosis, and as well as to the understanding of the clinical and pathological events involved.
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How to cite this article:

Lorena Ferreira Silva, Edson de Figueiredo Gaudencio Barbosa, Ernane de Paiva Ferreira Novaes, Jose Renato Junqueira Borges, Eduardo Mauricio Mendes de Lima and Marcio Botelho de Castro, 2016. Clinical and Pathological Changes in Sheep During a Monensin Toxicity Outbreak in Brasilia, Brazil. Asian Journal of Animal and Veterinary Advances, 11: 73-78.

DOI: 10.3923/ajava.2016.73.78

URL: https://scialert.net/abstract/?doi=ajava.2016.73.78

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