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Asian Journal of Animal and Veterinary Advances

Year: 2015 | Volume: 10 | Issue: 4 | Page No.: 173-178
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Authors

F. A. Al-Hizab

N. A.M. Al-Gabri

S. E.M. Barakat

Keywords

Research Article

Effect of Aflatoxin B1 (AFB1) Residues on the Pathology of Camel Liver

F. A. Al-Hizab, N. A.M. Al-Gabri and S. E.M. Barakat
This study was carried out to evaluate the potential effect of high Aflatoxin B1 (AFB1) residues on the pathology of livers of camels slaughtered at different abattoirs in AL-Ahsa region, Kingdom of Saudi Arabia. Aflatoxin residues were determined in a total number of 160 camel liver samples. Thirty seven (23.1%) liver samples showed residues of AFB1 higher than the standard permissible limit (spl. 0.05 ppb). Seventeen of these samples contained very high residues between 0.1-1.0 ppb. while twenty samples contained residues between 0.05-0.1 ppb. However, 123 (76.9%) liver samples showed AFB1 residues less than the standard permissible limits (spl). Small portions of the liver tissue from all animals were removed, weighed and preserved in 10% formalin solution and then embedded in paraffin wax. Pathological changes were observed in the liver tissues collected from all camels. Liver samples containing high AFB1 residues showed remarkable gross changes including fatty degeneration with variable areas of petechial hemorrhages, Congestion, fibrosis and large whitish focus of necrosis. However, mild gross changes were obtained in the liver samples containing medium AFB1 residues, between (0.05->0.1 ppb.) and no gross changes were obtained in the liver samples containing AFB1 residues bellow the standard permissible limits (spl). In addition the histopathological changes in the liver samples with high residues of AFB1 showed vacuolar degenerations, cholangitis, cirrhosis, bile duct carcinoma and hepatocellular carcinoma while hepatocytic fatty vacuolation, hydropic degeneration, congestion and mild degree of peribiliary cirrhosis were observed in the liver samples containing medium, AFB1 residues and no remarkable changes were seen in the liver samples containing AFB1 residues below the standard permissible limits (spl). These results revealed that aflatoxin residues may cause massive histopathological changes to the liver tissue of camels and caution should be exhibited in its use for human and animal consumption.
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