Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
Asian Journal of Animal and Veterinary Advances
  Year: 2009 | Volume: 4 | Issue: 6 | Page No.: 288-296
DOI: 10.3923/ajava.2009.288.296
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail
Isoflavone Aglycone from Fermented Soy Pulp Prevents Osteoporosis in Ovariectomized Rats
Go-Eun Hong, P.K. Mandal, Chang-Won Pyun, K. Choi, Soo-Ki Kim, Kyu-Ho Han, M. Fukushima, Ho-Chul Shin and Chi-Ho Lee

Abstract:
This study was done to investigate the effects of fermented soy pulp on the osteoporosis in ovariectomized rats. Sprague-Dawley female rats were randomly assigned to four groups as Sham Control (SC), Ovariectomized Control (OC), Ovariectomized and Soy Pulp (OSP) fed and Ovariectomized and Fermented Soy Pulp (OFSP) fed. All rats were fed on purified diets, supplemented with non-fermented and fermented soy pulp on basic diet for 7 weeks. It was observed that isoflavone aglycone was very high in soy pulp fermented for 12 h in comparison to non-fermented soy pulp. Body weight of the rats increased significantly (p<0.05) in comparison to other groups. Atrophy of uterus in OFSP group was significantly (p<0.05) prevented in comparison to OC group. The concentration of estradiol in OFSP group was higher than those of OC and OSP groups. The bone density in OFSP group was significantly (p<0.05) higher than those of OC and OSP groups. The histopathology indicated that OFSP group has better retarded the progress of osteoporosis than other groups. The results showed that isoflavone from the fermented soy pulp has prevented the osteoporosis in ovariectomized rats must be due to its estradiol like function. It is expected that the fermented soy pulp might serve as a functional food in osteoporosis of postmenopausal women.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Soybean Sprouts Inhibit Bone Turnover in Ovariectomized Rats
  •    Effects of Fermented Pueraria radix by Lactobacillus acidophilus on Lipid and Bone Metabolism in Ovariectomized Rats
  •    Fermentation Increases Isoflavone Aglycone Contents in Black Soybean Pulp
How to cite this article:

Go-Eun Hong, P.K. Mandal, Chang-Won Pyun, K. Choi, Soo-Ki Kim, Kyu-Ho Han, M. Fukushima, Ho-Chul Shin and Chi-Ho Lee, 2009. Isoflavone Aglycone from Fermented Soy Pulp Prevents Osteoporosis in Ovariectomized Rats. Asian Journal of Animal and Veterinary Advances, 4: 288-296.

DOI: 10.3923/ajava.2009.288.296

URL: https://scialert.net/abstract/?doi=ajava.2009.288.296

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 

       

       

Curve Bottom