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Asian Journal of Animal and Veterinary Advances

Year: 2009 | Volume: 4 | Issue: 4 | Page No.: 191-199
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Authors

N. Atasoy

N. Mercan

C. Atalay

E. Bayram

A. Tas

Keywords

Clinical Report

Evaluation of a Mixture of Thiopental-Guafinesine-Metedomidine and Sevoflurane Anesthesia in Horses

N. Atasoy, N. Mercan, C. Atalay, E. Bayram and A. Tas
The anesthetic and cardiopulmonary effects of a combination of continuous intravenous infusion using a mixture of 6 g L–1 thiopental-75 g L–1 guafinesine-3 mg L–1 metedomidine (0.30 mL/kg/h) and Oxygen-Sevoflurane (OS) anesthesia (TGM-OS anesthesia) in horses were evaluated. The concentration of sevoflurane (Sevo) required maintaining surgical anesthesia was around 1.5% in TGM-OS and 3.3% in OS anesthesia. Mean Arterial Blood Pressure (MABP) was maintained at around 77 mm Hg under TGM-OS anesthesia, while dobutamine (0.43±0.13 μg kg–1) infusion was necessary to maintain MABP at 60 mmHg under OS anesthesia. No apparent complication was observed during and after anesthesia in all cases. Recovery from anesthesia under TGM-OS anesthesia was very calm and smooth. The times required for the horse to return both sternal and standing position in group under TGM-OS anesthesia tended to be shorter than group under OS anesthesia which statistical differences were p<0.05 and p<0.01, respectively. Thiopental Guafinesine-Metedomidine and Oxygen-Sevoflurane anesthesia (TGM-OS anesthesia) may be useful for prolonged equine anesthesia because of its minimal cardiopulmonary effects and good recovery from anesthesia.
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Dr W.P Mshelia Reply

This paper has answered alot of scientific questions.

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