Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
Asian Journal of Animal Sciences
  Year: 2012 | Volume: 6 | Issue: 6 | Page No.: 300-308
DOI: 10.3923/ajas.2012.300.308
Cimicifuga racemosa Potentiates Antimuscarinic, Anti-adrenergic and Antihistaminic Mediated Tocolysis of Buffalo Myometrium
R. Rathore, A. Rahal and R. Mandil

Abstract:
Ethnoveterinary practices hold a promising scientific resource and can have far-reaching implications on economic development and enhancement of veterinary health care system. The present study was undertaken to evaluate the oxytocic/tocolytic activities of Cimicifuga racemosa (C. racemosa) roots extracts on isolated uterine strips of pregnant buffalo. Hot methanolic extraction of authenticated roots of C. racemosa was done using soxhlet extractor. Hot methanolic extract of C. racemosa roots was found to exert a myometrial relaxant effect which was potentiated after inhibition of excitatory muscarinic, alpha and beta adrenergic, H1-histaminergic and 5-HT receptors. Further studies are required on mechanistic aspects of tocolytic effect of C. racemosa particularly to elucidate the involvement of Ca2+ and K+ channels, NO and other signaling mechanisms including second messengers.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Pharmacological Properties of Cassia nigricans Vahl Against Human and Veterinary Diseases
  •    Evaluation of the Proposed Inhibitory Effect of the Aqueous Stem-Bark Extract of Ficus exasperata on Uterine Preparations in vitro
  •    Effect of Different Doses of Oxytocin at Delivery on Suffering and Survival of Newborn Pigs
  •    Atropine Sulphate Induced Changes in Uterine, Adrenal, Liver and Thyroid Gland in Female Albino Rats
How to cite this article:

R. Rathore, A. Rahal and R. Mandil, 2012. Cimicifuga racemosa Potentiates Antimuscarinic, Anti-adrenergic and Antihistaminic Mediated Tocolysis of Buffalo Myometrium. Asian Journal of Animal Sciences, 6: 300-308.

DOI: 10.3923/ajas.2012.300.308

URL: https://scialert.net/abstract/?doi=ajas.2012.300.308

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 

       

       

Curve Bottom