Tong-Han Lan
Department of Biomedical Engineering, Huazhong University of Science and Technology,
Wuhan 430074, Peoples Republic of China
Xian-Ming Liu
Department of Biomedical Engineering, South-central National University,
Wuhan, 430074, Peoples Republic of China
ABSTRACT
In present study, a concentration-dependent effect of Selenium on rat dorsal root ganglion neurons was characterized using whole-cell patch-clamp recording. Among about 52% of the cells tested, the amplitude of membrane ion current increased, after administration of Selenium. In the presence of 0.001 nM (nanomolar) Selenium, the reversal potential and membrane conductance were changed. The above-mentioned actions suggest that selenium may play a physiological role in regulating the excitatory action on mammalian neurons.
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How to cite this article
Tong-Han Lan and Xian-Ming Liu, 2005. Different Concentration Selenium-modulated Action on Rat Dorsal Root Ganglion
Neurons. Pakistan Journal of Biological Sciences, 8: 855-859.
DOI: 10.3923/pjbs.2005.855.859
URL: https://scialert.net/abstract/?doi=pjbs.2005.855.859
DOI: 10.3923/pjbs.2005.855.859
URL: https://scialert.net/abstract/?doi=pjbs.2005.855.859
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