M. A. Geidam
Department of Biochemistry, College of Medical Sciences,
University of Maiduguri, P.M.B. 1069 Maiduguri, Barno State, Nigeria
G. I. Adoga
Department of Biochemistry, Faculty of Medical Sciences, University of Jos,
P.M.B. 2084 Jos, Plateau State, Nigeria
F. A. Sanda
Department of Biochemistry, College of Medical Sciences,
University of Maiduguri, P.M.B. 1069 Maiduguri, Barno State, Nigeria
ABSTRACT
This study was undertaken to assess the effect of 100 mg kg-1 body weight of aqueous stem bark extract of Cissus populnea on serum enzyme levels in normal and alloxan induced diabetic rats. The four weeks experimental protocol involving intragastric administration of the extract revealed a significant increase (P<0.05) in the level of serum alkaline and total acid phosphatase only as a result of diabetes induction. The treatment with Cissus has also revealed a significant increase (P<0.05) in the level of serum acid phosphatase. However, there were no significant differences in the levels of aspartate and alanine aminotranferases as a result of both diabetes induction and Cissus populnea treatment.
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How to cite this article
M. A. Geidam, G. I. Adoga and F. A. Sanda, 2004. Effects of Aqueous Stem Bark Extract of Cissus populnea on Some Serum Enzymes in Normal and Alloxan Induced Diabetic Rats. Pakistan Journal of Biological Sciences, 7: 1427-1429.
DOI: 10.3923/pjbs.2004.1427.1429
URL: https://scialert.net/abstract/?doi=pjbs.2004.1427.1429
DOI: 10.3923/pjbs.2004.1427.1429
URL: https://scialert.net/abstract/?doi=pjbs.2004.1427.1429
REFERENCES
- Belfiore, F., E. Napoli and L.L. Vecchio, 1972. Increased activity of some enzymes in serum in cases of severely decompensated diabetes with and without Ketoacidosis. Clin. Chem., 18: 1403-1406.
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