Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2013.826.843Mahima M. IngleAbhijeet VermaAmit Kumar TiwariRuchi KarthikK. ChakrabortySandip DebRajib RajagunalanS. RathoreRajesh DhamaKuldeep 1220131617There are ongoing trends of immunomodulation to combat a vast
range of human and animal diseases including the incurable diseases like viral
diseases, cancers, autoimmune diseases and inflammatory conditions. Animate
as well as non-animate factors, surrounding us are interacting with our immune
system. A balanced diet should contain all essential components from energy
to vitamin and trace minerals. Each of these constituent has a very special
effect on the immune system starting from their development to active role in
immunity therefore, the outcome of their deficiency often ends in disease. Edible
items which we consume like various vegetables, spices, herbs, fruits etc.,
are also equally responsible in manipulation of our system either in positive
or negative way. Water has biggest share in our body and acts as the main medium
to support the activities of the different system of body without exception
of immune system. Proper environmental temperature is essential to maintain
bodys functions and experiments carried out regarding the effect of temperature
suggest that extremes of the temperature are often cause immunosuppression directly
by acting on the cells of immunity or indirectly through inducing stress and
thereby increasing production of catecholamine which are potent anti-immune
molecules. Various pathogenic as well as non-pathogenic bacteria cause immune
suppression and immune potentiation, respectively. Proper exercise hold a prime
position in the healthy life as it supports immunity and keeps disease away.
The present review deals with all these immunomodulators having both positive
and negative impact on the health status of an individual.]]>Hannan, A., T. Humayun, M.B. Hussain, M. Yasir and S. Sikandar,2010In vitro antibacterial activity of onion (Allium Cepa) against clinical isolates of Vibrio Cholerae.]]>22160163Actis, G.C., R. Pellicano, E. Bugianesi, M. Lagget and M. Rizzetto,200854239242Ahamad, M.N., M. Saleemullah, H.U. Shah, I.A. Khalil and A.U.R. Saljoqi,200723767770Akbar, N.A. and M.A. Zacharek,201119224228Al-Mamun, H. Khatun, R. Islam, L. Nahar, K.M. Shams-Ud-Doha and F.A. Ripa,2011piper longum linn. Leaves.]]>228742879Al-Suhaimi, E.A., N.A. Al-Riziza and R.A. Al-Essa,201139215231Aranha, I., F. Clement and Y.P. Venkatesh,2012Tinospora cordifolia).]]>139366372Arunachalam, K., H.S. Gill and R.K. Chandra,2000Bifi dobacterium lactis (HN019).]]>54263267Ashkenazy, Y., S. Moshonov, G. Fischer, D. Feigel and A. Caspi et al.,19909283288Chandua, A.N., S. Kumar, C. Bhattacharjeeb, S. Debnathb and K.K. Kannanc,2011Aloe Vera (Linn).]]>21922Awodele, O., S.O. 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