Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2013.751.758RahalAnu AhmadA. H. KumarAmit Mahima VermaAmit Kumar ChakrabortySandip DhamaKuldeep 1220131616Every time a drug is administered to the animal to treat an
ailment, no matter whether it is acute or chronic manifestation, it usually
goes together with some other prescription medicine, OTC (Over the counter)
formulation, herbs or even food. All the xenobiotics such as drugs, toxins and
food components as well as the endogenous compound that are formed in the animal
body as a routine phenomenon exert a stimulatory or inhibitory effect on the
different physiological and biochemical processes going in the body. These effects
may alter the normal metabolism and/or drug transport or its efficacy drastically
and thus expose the man and animals to the risk of a potentially dangerous interaction.
The present review discusses these potential reactions and their mechanisms
that help in navigating the hazardous combinations of drugs with other medicines,
food, herbs, vitamins and minerals with confidence.]]>Ansari, J.A.,20102326331Arnaud, L., A. Mathian, J. Boddaert and Z. Amoura,201229181189Chaudhary, M., A.K. Garg, G.K. Mittal and V. Mudgal,2010133217226Davis, M.W., S. Wason and J.L. Digiacinto,201328176183Farukbhai, N.M.,20102010Freudenthaler, S., I. Meineke, K.H. Schreeb, E. Boakye, U. Gundert-Remy and C.H. Gleiter,199846541546Garcia Fernandez, V., M. Garrido Arevalo, E. Labrada Gonzalez and F.J. Hidalgo Correas,2013377273Garcia-Barrera, T., J.L. Gomez-Ariza, M. Gonzalez-Fernandez, F. Moreno, M.A. Garcia-Sevillano and V. Gomez-Jacinto,201240322372253Hanigan, M.H., B.L. Dela Cruz, S.S. Shord, P.J. Medina, J. Fazili and D.M. Thompson,201189114119Ip, T.K., P. Aebischer and P.M. Galletti,198834351355Kumar, A. and A. Rahal,20052005pp: 5758Kumar, A., A. Rahal, R. Ragvendra, A. Prakash, R. Mandil and S.K. Garg,2012710061013Kumar, P., A.H. Ahmad, A. Rahal and K.P. Singh,200985255Kumar, P., A.H. Ahmad, A. Rahal and K.P. Singh,2011719Lynch, T. and A. Price,200776391396Mahendra Kumar, B.J., M. Kumaraswamy and L. Mahadevamma,201143136Mahima, A. Rahal, R. Deb, S.K. Latheef and H.A. Samad et al.,201215754774Mahima, A.K. Verma, A. Kumar, A. Rahal, V. Kumar and D. Roy,201215418425Alavijeh, M.S., M. Chishty, M.Z. Qaiser and A.M. Palmer,20052554571Rahal, A. and J.K. Malik,2010931923Rahal, A. and J.K. Malik,201195179183Rahal, A., A. Kumar, A.H. Ahmad and J.K. Malik,200884452456Rahal, A., A. Kumar, A.H. Ahmad, and J.K. Malik,200773242245Rahal, A., A. Kumar, A.H. Ahmad, J.K. Malik and V. Ahuja,200629321324Rahal, A., V. Singh, D. Mehra, S. Rajesh and A.H. Ahmad,2009Podophyllum hexandrum in alleviation of immobilization stress-induced oxidative damage in rat.]]>2110115Rathore, R., A. Rahal and R. Mandil,2012Cimicifuga racemosa potentiates antimuscarinic, anti adrenergic and antihistaminic mediated tocolysis of buffalo myometrium.]]>6300308Rathore, R., A. Rahal, R. Mandil, A. Prakash and S.K. Garg,2012Cimicifuga racemosa and Mimosa pudica.]]>42274278Rodrigues, R.J.,20007813441351Singh, V., A. Rahal, K.P. Singh and A.H. Ahmad,2009Withania somnifera roots on antioxidant defence in mercury induced toxicity in HepG2 cell line.]]>56572Singh, V., A. Rahal, K.P. Singh and A.H. Ahmad,201096467Gysin, S., M. Salt, A. Young and F. McCormick,20112359372Thaler, S., C. Neumeier and G. Flury,20132013Kirking, D.M., J.W. Thomas, F.J. Ascione and E.L. Boyd,19862218Trumic, E., N. Pranjic, L. Begic, F. Becic and M. Asceric,201266243248Valiyil, R. and L. Christopher-Stine,201012213220Verma, S., A.H. Ahmad, A. Rahal and K.P. Singh,2009369396Verma, S., A.H. Ahmad, K.P. Singh and A. Rahal,2011105860Wachter, R.M. and A. Verghese,2012308977978