Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2012.92.97Tecoma stans Bignoniaceae]]>Al-AzzawiAmad M.22012152Tecoma stans (Bignoniaceas) is a central and south American tree used for the control of diabetes. This plant is cultivated in Iraq. The dried leaves were soaked in ethanol and water separately for 3 days then filtered and dried. The genotoxic potential of Tecoma stans was studied by in vivo and in vitro system. This study examined the genotoxic activity of aqueous and ethanolic extracts on bone marrow cells from BALB/c mice through evaluation of mitotic index and chromosomal aberrations and cytotoxic effect of the two extracts on Mouse Embryo Fibroblast (MEF) cell line. No alteration in the total number of chromosomal aberrations or the number of cells with chromosomal aberrations observed and percentage of mitotic index at the concentrations tested remained unchanged. The higher concentrations used of the plant extracts had a cytotoxic effect on the MEF cell line. Both extracts had no significant clastogenic effect in vivo but showed cytotoxic effects on mouse embryo in vitro, caution should be exercised in the use of this substance as a medicine.]]>Jones, G.H., M. Fales and W.C. Wildman,19636397400Costantino, L., L. Raimondi, R. Pirisino, T Brunetti and P. Pessotto et al.,2003Tecoma stans alkaloids.]]>58781785Marzouk, M., A. Gamal-Eldeen, M. Mohamed and M. El-Sayed,2006Tecoma stans.]]>61783791Aguilar-Santamaria, L., G. Ramirez, P. Nicasio, C. Alegria-Reyes and A. Herrera-Arellano,2009Tecoma stans (L.) Juss. ex Kunth.]]>124284288Alonso-Castro, A.J., R. Zapata-Bustos, J. Romo-Yanez, P. Camarillo-Ledesma, M. Gomez-Sanchez and L.A. Salazar-Olivo,2010Tecoma stans (L.) Juss. ex Kunth (Bignoniaceae) and Teucrium cubense Jacq (Lamiaceae) induce the incorporation of glucose in insulin-sensitive and insulin-resistant murine and human adipocytes.]]>12716Tan, M.L., S.F. Suleiman, N. Najimuddin, M.R. Samian and T.S. Tengku-Muhammad,200596287294Costa-Lotufo, L.V., M.T.H. Khan, A. Ather, D.V. Wilke and P.C. Jimenez et al.,2005992130Paniagua, P.R., M.E. Bujaidar, R.S. Cadena, M.D. Jasso and G.J. Perezet al.,20052005242247Ford, C.E. and J.L. Hamerton,195631247251Burim, R.V., R. Canalle, J.L.C. Lopes and C.S. Takahashi,1999in vitro and in vivo.]]>22401406Mohammed, B.M., K.J. Karim and N.Y. Yaseen,200912216226Shubber, E.K. and A.S. Juma,200442182187Maranon, D.G., A.O. Laudicina and M. Muhlmann,2004In situ DNAse I sensitivity assay indicates DNA conformation differences between CHO cells and the radiation-sensitive CHO mutant IRS-20.]]>104100103Cunha, R.A.F., C.P. Koiffman, D.H. Souza and K. Takei,199730749757Al-Shamery, A.M.H.,20032003Freshney, R.I.,19943rd Edn.,pp: 267-308pp: 267-308Mahony, D.E., E. Gilliat, S. Dawson, E. Stockdale and S.H. Lee,19895521412143Chiang, L.C., W. Chang, M.Y. Chang and C.C. Lin,2003In vitro cytotoxic, antiviral and immunomodulatory effects of Plantago major and Plantago asiatica.]]>31225234Mather, J.P. and P.E. Roberts,19981st Edn.,Pages: 260Pages: 260Hamburger, M. and K. Hostettmann,19913038643874Beltrame, F.L., G.L. Pessini, D.L. Doro, B.P.D. Filho, R.B. Bazotte and D.A.G. Cortez,2002Cissus sicyoides.]]>452125Suffredimi, I.B., H.S. Sader, A.G. Goncalves, A.O. Reis, A.C. Garles, A.D. Varella and R.N. Younes,200437379384Zimmermann, M.,198316109110Kasuba, V., K. Sentija, V. Garaj-Vrhovac and A. Fucic,1995346187193