Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2012.255.258ShariatpanahiMaryam Vahdat ShariatpanahiZahra Vahdat ShahbaziShaahin MoshtaqiManoochehr 52012155The metabolic syndrome has been recognized as a proinflammatory
state and inflammatory markers are associated with an increased risk for subsequent
cardiovascular disease and type 2 diabetes. The aim of this clinical trial study
was to evaluate the effect of Ramadan fasting on High-sensitive C-reactive Protein
(hs-CRP) and fibrinogen levels in metabolic syndrome. Sixty five male with metabolic
syndrome who were admitted to Hospital were selected for the study. Waist circumference,
BMI, FPG, HDL-C, TG, fibrinogen and hs-CRP were evaluated before and after month
of Ramadan. The duration of study was thirty days. The dietary intake was estimated
by 24 h recall before and after fasting. Metabolic syndrome was diagnosed using
the ATP III criteria. FPG, HDL-C, fibrinogen, hs-CRP, BMI and waist circumference
were decreased significantly after study (p = 0.005, p = 0.002, p = 0.02, p
= 0.01, p = 0.01, p = 0.01, respectively). There was no change in serum TG level
(p = 0.21). Simple linear regression analysis demonstrated that after fasting,
hs-CRP was related to waist circumference and BMI (r = 0.388, p = 0.01 and r
= -0.439, p = 0.02, respectively). Change in the number and timing of meals
and portioning the entire intake into two without changing the total energy
consumption may have beneficial effects on anthropometry measures and inflammatory
markers of metabolic syndrome.]]>Aksungara, F.B., A.E. Topkayab and M. Akyildizc,2007518895Bogdan, A., B. Bouchareb and Y. Touitou,20016816071615Esposito, K., R. Marfella, M. Ciotola, C. Di Palo and F. Giugliano et al.,200429214401446Festa, A., R. D’Agostino, G. Howard, L. Mykkanen, R.P. Tracy and S.M. Haffner,20001024247Festa, A., R. D'Agostino Jr., R.P. Tracy and S.M. Haffner,20025111311137Hu, F.B., J.B. Meigs, T.Y. Li, N. Rifai and J.E. Manson,200453693700Inoue, S., P. Zimmet, I. Caterson, C. Chunming and Y. Ikeda et al.,2000Pages: 56Pages: 56Kassab, S., T. Abdul-Ghaffar, D.S. Nagalla, U. Sachdeva and U. Nayar,200424345349Koh, K.K., S.H. Han and M.J. Quon,20054619781985Minehira, K. and L. Tappy,20025612641269Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults,200128524862497Nelson, W., L. Cadotte and F. Halberg,1973144766769Pradhan, A.D., J.E. Manson, N. Rifai, J.E. Buring and P.M. Ridker,2001286327334Ridker, P.M., J.E. Buring, N.R. Cook and N. Rifai,2003107391397Ridker, P.M., P.W.F. Wilson and S.M. Grundy,200410928182825Rutter, M.K., J.B. Meigs, L.M. Sullivan, R.B. D'Agostino Sr. and P.W.F. Wilson,2004110380385Salehi, M. and M. Neghab,200710968971Shariatpanahi, Z.V., M.V. Shariatpanahi, S. Shahbazi, A. Hossaini and A. Abadi,2008100147151Woloshin, S. and L.M. Schwartz,200535216111613