Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2012.103.107NikookarSeyed Hasan HajheydariZohreh Moosa-KazemiSeyed Hasan MahmoudiMitra ShahmohammadiSoheila 22012152Dermatitis caused by stimulation of beetle paederus, is a common health problem in Northern and some southern parts of Iran. Since by now, traditional medicine and some corticosteroid agents have been used for treatment of dermatitis caused by beetle paederus. Because, there are few researches about classical treatment of the disease at academic level, this study planned to compare the effectiveness of triamcinolone ointment and atorvastatin tablet with placebo in treatment of paederus dermatitis in Northern Iran. A randomized double-blind clinical trial was carried out on 30 patients referred to the hospital and clinics at Sari and Neka countries in Northern Iran during 6 months. Patients were randomly divided into two therapeutic equal groups. The first group was triamcinolone ointment twice a day and a placebo atorvastatin tablet daily. The second group was oral atorvastatin one tablet (20 mg) daily and a placebo triamcinolone ointment twice a day. In Seventh day of visits, therapeutic response of the patients in triamcinolone and atorvastatin group were 93.33 and 80%, respectively. No significant differences were found in therapeutic outcome between the two groups (p>0.05). The results showed both of triamcinolone ointment and oral atorvastatin had similar effect on paederus dermatitis. Because the paederus dermatitis is a self-limited disease use of topical therapy for treatment of the disease is recommend.]]>Schofield, S.,20052005Zargari, O., A. Kimyai-Asadi, F. Fathalikhani and M. Panahi,2003Paederus dermatitis in northern Iran: A report of 156 cases.]]>42608612Rahmah, E. and M.J. Norjaiza,2008305356Al-Dhalimi, M.A.,2008Paederus dermatitis in Najaf Province of Iraq.]]>2914901493Gnanaraj, P., V. Venugopal, M.K. Mozhi and C.N. Pandurangan,2007Paederus dermatitis in a suburban hospital in South India: A report of 123 cases and review of literature.]]>57297300Kumar, P., R.C. Gharami, A. Mondal, K. Ghosh,2010205759Smith, K.J., J.S. Graham, R.B. Moeller, C.V. Okerberg, H. Skelton and C.G. Hurst,199522260268Nikbakhtzade, M.R.,20052005Frank, J.H. and K. Kanamitsu,1987Paederus, sensu lato (Coleoptera: Staphylinidae): Natural history and medical importance.]]>2155191Law, M.R., N.J. Wald and A.R. Rudnicka,200332614231427Downs, J.R., M. Clearfield, S. Weis, E. Whitney and D.R. Shapiro et al.,199827916151622Ridker, P.M., N. Rifai, M.A. Pfeffer, F.M. Sacks and L.A. Moye et al.,199898839844Steinberg, D.,200549995998Andalib, S., M. Ziaee, N. Maleki, H. Maljaei, H. Hamzeiy and A. Garjani,20072714Casey, P.J.,1995268221225Davoudi, S.M., P. Rostami, S.B. Sadr, E. Khabiri and S.N. Emadi,20069217220Armstrong, R.K. and J.L. Winfield,1969Paederus fuscipes dermatitis: An epidemic on Okinawa.]]>18147150