Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2011.552.557DayerMohammad RezaMard-SoltaniMaysam DayerMohammad SaaidAlaviSayed Mohammad Reza92011149Increased risk of vascular diseases in hypercoagulable states is assumed to be the major cause for prevalence of vascular problems in type 2 diabetes mellitus patient. The present study was undertaken to explore the basis underlying the correlation between the aforesaid three coagulation factors with reference to the relevant mechanistic findings using statistical calculation. Our findings showed that the correlation between each pairs of coagulation factors, FV, FVIII and vWF could be easily interpreted using previously characterized interactions between these factors. Also, given the sequence similarities between FV and FVIII as well as the results of this study, it was indicated, for the first time, that FV may bind to vWF in the same way as FVIII binds. This finding seems to be of great importance to be evaluated through experimental techniques.]]>Asselta, R. and F. Peyvandi,200935382389Asselta, R., M.L. Tenchini and S. Duga,200642634Behnam-Rassouli, M., M.B. Ghayour and N. Ghayour,201010411423Bowen, D.J., R.M. Maclean, S. Pellard and P.W. Collins,2001113655657Camire, R.M. and M.H. Bos,2009719511961Duffy, T.C., R. Kirby and E. Rudloff,2004148499Eikenboom, J.C., G. Castaman, P.W. Kamphuisen, F.R. Rosendaal and R.M. Bertina,200287252257Fang, H., L. Wang and H. Wang,2007119113Fuentes-Prior, P., K. Fujikawa and K.P. Pratt,20023313339Hajifathali, A., B. Kazemi, A. Pourfathollah, G.R. Lari and R. Chegeni,2005812721274Hameed, A., S.A. Malik, F. Rabbi, A. Sharif and N. Ahmad et al.,20022710714Ma, E.S., C.L. Wong, H.Y. Lam, C.L. Wang and S.Y. Ma,2007LMAN1 gene.]]>139509511Mard-Soltani, M., M.R. Dayer, G. Ataie, A.A. Moazedi, M.S. Dayer and S.M.R. Alavi,20111244254Ni Ainle, F., R.J. Preston, P.V. Jenkins, H.J. Nel and J.A. Johnson et al.,200911416581665Pipe, S.W.,20091511871196Rezaeian, Z., G. Torkman, F. Nad-Ali, R. Ravanbod and A.A. Pourfathollah et al.,2006920322039Rondaij, M.G., R. Bierings, E.L. van Agtmaal, K.A. Gijzen and E. Sellink et al.,20081125663Suzuki, H., M. Shima, K. Nogami, Y. Sakurai and K. Nishiya et al.,2006413541360Van den Biggelaar, M., E.A.M. Bouwens, N.A. Kootstra, R.P. Hebbel, J. Voorberg and K. Mertens,200994670678Van den Biggelaar, M., A.B. Meijer, J. Voorberg and K. Mertens,200911331023109Wigren, E., J.M. Bourhis, I. Kursula, J.E. Guy and Y. Lindqvist,2010584878882Zheng, C., H.H. Liu, S. Yuan, J. Zhou and B. Zhang,201011656985706