Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2009.908.913IlboudoD. SimporeJ. SanouD.S. KarouD. SiaD.J. OuermiD. BisseyeC. SagnaT. OdoliniS. BuelliF. PietraV. PignatelliS. GnoulaC. NikiemaJ.B. CastelliF. 1220091212In Sub-Saharan Africa, many HIV infected people are co-infected with Human Herpes Virus 8 (HHV-8). Therefore, the present study aimed to: (1) identify the pregnant women co-infected by HIV and HHV-8 at Saint Camille Medical Centre; (2) use three molecules (Zidovudine, Nevirapine and Lamivudine) to interrupt the vertical transmission of HIV and (3) use the PCR technique to diagnose children, who were infected by these viruses, in order to offer them an early medical assistance. A total of 107 pregnant women, aged from 19 to 42 years were diagnosed to be HIV positive at Saint Camille Centre; among them 13 were co-infected with HHV-8. All included women received the HAART. Two to six months after childbirth their babies underwent PCR diagnosis for HIV and HHV-8. The results revealed that, among these mothers, 68.2% were housewives, 34.6% were illiterates and 60.7% did not have university degree. The prevalence of HHV-8 among these pregnant women was 12.15% and the rate of vertical transmission of both HIV and HHV-8, was 0.0%. The issue of this study revealed that the antiretroviral therapy increased the mother CD4 T-cells, prevented the transcription of the mRNA of HHV-8 and blocked HIV vertical transmission.]]> Boivin, G., C. Hankins, N. Lapointe, S. Walmsley and A. Gaudreau et al.,20001410731075Brayfield, B.P., S. Phiri, C. Kankasa, J. Muyanga and H. Mantina et al.,2003187559568Calabro, M.L., P. Gasperini, J.R. Fiore, M. Barbierato and G. Angarano et al.,200193154156Calabro, M. L., P. Gasperini, M. Barbierato, L. Ometto and M. Zanchetta et al.,200085296297Caselli, E., M. Galvan, E. Cassai, A. Caruso, L. and L. Sighinolfi et al.200510627902797Caselli, E., M. Galvan, F. Santoni, A. Rotola and A. Caruso et al.,20038411231131Caselli, E., P. Menegazzi, A. Bracci, M. Galvan and E. Cassai et al.,20018219651970Ceffa, S., E. Buonomo, A.M. Altan, F. Erba and P. Germano et al.,200719519523Chang, Y., E. Cesarman, M.S. Pessin, F. Lee, J. Culpepper and D.M. Knowles,199426618651869Chironna, M., M.A.Tosatti, I.M. Di Gangi, A. Sallustio and C. Germinario et al.,200678933937Coluzzi, M., M.L. Calabro, D. Manno, L. Chieco-Bianchi L and T.F. Schulz et al.,200317461464Cook-Mozaffari, P., R. Newton, V. Beral and D.P. Burkitt,19987815211528Deschamps, M.M., F. Christmas, J. Catch , J.G. Devieux and G. Midsummer's Day et al.,2009252430Dukers, N.H. and G. Rezza,20031717171730Eltom, M.A., A. Jemal, S.M. Mbulaiteye, S.S. Devesa and R.J. Biggar,20029412041210Ensoli, B., G. Barillari, S.Z. Salahuddin, R.C. Gallo and F. Wong-Staal,19903458486Fiore, J.R., A. Volpe, M.A. Tosatti, L. De Valentin and A. Favia et al.,200472656660Fujii, T., H. Taguchi, H. Katano, S. Mori and T. Nakamura et al.,199957159162Gessain, A., P. Mauclere, M. van Beveren, S. Plancoulaine and A. Ayouba et al.,199981189192Gregoire, L.J., G. Auregan and H. Van Renterghem,20002000Hyun, T.S., C. Subramanian, M.A. Cotter, R.A. Thomas and E.S. Robertson,20017587618771Ilboudo, D., D. Karou, W.M.C. Nadembega, A. Savadogo and O.D.S. Pignatelli et al.,20071028312837Kaposi, M.,198232342347Lampinen, T. M., S. Kulasingam, J. Min, M. Borok and L. Gwanzura et al.,200018117851790Lyall, E.G., G.S. Patton, J. Sheldon, C. Stainsby and J. Mullen et al.,199918795799Mancuso, R., R. Biffi, M. Valli, M. Bellinvia and A. Tourlaki et al.,20088021532160Mantina, H., C. Kankasa, W. Klaskala, B. Brayfield and J. Campbell et al.,200194749752Mayama, S., L.E. Cuevas, J. Sheldon, O.H. Omar and D.H. Smith et al.,199877817820Meda, N, P. Msellati, C. Welffens-Ekra, M. Cartoux and M. Leroy et al.,19977115125Medrano, J. and V. Soriano,2009132505506Mercader, M., B. Taddeo, J.R. Panella, B. Chandran and B.J. Nickoloff et al.,200015619611971Minhas, V., K.L. Crabtree, A. Chao, T.J. M'soka and C. Kankasa et al.,2008168311320O'Brien, T.R., D. Kedes, D. Ganem, D.R. Macrae, P.S. Rosenberg and J. Molden,199918010101017Plancoulaine, S., L. Abel, M. van Beveren, D. A. Tregouet and M. Joubert et al.,200035610621065Ranger-Rogez, S., S. Alain and F. Denis,200250568575Shaheen, F., A.V. Sison, L. McIntosh, M. Mukhtar and R.J.J. Pomerantz,19992154166Simpore, J., D. Ilboudo, D. Karou, V. Pietra and M. Granato et al.,200669398Simpore, J., V. Pietra, A. Savadogo, S. Pignatelli and J.B. Nikiema et al.,200678148152Simpore, J., V. Pietra, S. Pignatelli, D. Karou and W.M.C. Nadembega et al.,200779873879Strathdee, S.A., P.J. Veugelers and P.S. Moore.1996105157Tsai, W.H., Y.M. Lee, B. Ing-Tiau Kuo, C.K. Ho and P.T. Liao et al.,20051149598Varthakavi, V., R.M. Smith, H. Deng, R. Sun and P. Spearman,2002297270280Viviano, E., F. Vitale, A.M. Perna, F. Cataldo F and A. Firenze et al.,2009321115Whitby, D., N.A. Smith, S. Matthews, S. O'Shea and C.A. Sabin et al.,1999179234236Zavos, G., M. Gazouli, I. Papaconstantinou, J.C. Lukas and A. Zografidis et al.,200519729732Zeng, Y., X. Zhang, Z. Huang, L. Cheng and S. Yao et al.,20078124012417