Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2009.877.881AmirianM. RajaiM. AlaviA. ZareS. AliabadiE. 1120091211The objective of this study was to compare the efficiency
of lidocaine with that of plain saline for paracervical pain relief during
fractional curettage. The double-blind randomized clinical trial was performed
on 150 patients presenting from 2004 to 2005 for curettage. The patients
were assigned randomly in two groups to receive lidocaine 1% or normal
saline. Number of patients at each group was 75 women. The pain intensity
was assessed in four stages: 1) after speculum insertion, 2) during cervical
dilatation, 3) during curettage and 4) 30 min after curettage completion.
The pain intensity was graded as 0 to 100 according to the Likert Scale.
The Mean±SD of pain intensity after speculum insertion, during
dilatation, during curettage and 30 min after curettage in lidocaine group
were 11.33±9.70, 24.93±15.36, 37.00±17.35, 6.47±6.42
and in normal saline group were 11.73±9.81, 28.20±13.19,
49.47±21.55 and 7.33±6.22, respectively. There was no significant
difference between pain intensity after speculum insertion, during dilatation
and during 30 min after curettage but there was a significant difference
in pain intensity during curettage between lidocaine 1% group and normal
saline group (p<0.05). Normal saline is as effective as lidocaine 1%
in low pain in curettage (distention of nerve capsule) but when increase
pain in curettage (third time point), lidocaine 1% is more effective than
normal saline. Nerve capsule distention is not the only factor for pain
control in paracervical block and analgesic agent is still an important
factor.]]>Ader, L., B. Hansson and G. Wallin,199041133138Api, O., O. Unal, V. Ugurel, M.B. Emeksiz and C. Turan,200963105111Borgatta, L. and D. Nickinovich,199742287293Cetin, A. and M. Cetin,1997568587Chanrachakul, B., P. Likittanasombut, P. O-Prasertsawat and Y. Herabutya,200198592595Donati, S., E. Medda, S. Proietti, L. Rizzo, A. Spinelli, D. Subrizi and M.E. Grandolfo,199670145149Edelman, A., M.D. Nichols, C. Leclair and J.T. Jensen,2006107269275Edelman, A., M.D. Nichols, C. Leclair, S. Astley, K. Shy and J.T. Jensen,200410312671272Eser, E., H. Yuksel, H. Baydur, M. Erhart and G. Saatli et al.,200819409417Gómez, P.I., H. Gaitan, C. Nova and A. Paradas,2004103943951Guney, M., B. Oral, G. Bayhan and T. Mungan,200714304310Guney, M., B. Oral and T. Mungan,2006108119123Lau, W.C., W.K. Lo, W.H. Tam and P.M. Yuen,1999106356359Miller, L., M.P. Jensen and M.A. Stenchever,199687600604Ng, E.H., O.S. Tang, D.K. Chui and P.C. Ho,19991427832787Phittayawechwiwat, W., C. Thanantaseth, N.I. Ayudhya, P. O-Prasertsawat and J. Kongprasert,20079010531057Rattanachaiyanont, M., P. Leerasiri and S. Indhavivadhana,2005106533539Titapant, V., S. Chawanpaiboon and K. Boonpektrakul,200386131135Wiebe, E.R., K.J. Trouton and E. Savoy,20052020252028Wong, C.Y., E.H. Ng, S.W. Ngai and P.C. Ho,20021712221225