Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2007.905.909EftekhariM.H. KhosraviH. Mozaffari MazloomZ. AhmadiA. 62007106The present research was conduted to examine the relationship between thyroid function and body mass index. A cross-sectional study was carried out in Lar province and its' vicinity in south of Iran. By stepwise random sampling from all public girls' high schools, 227 high school participants (aged 12-21) were selected. Serum samples were collected and assayed for Triiodothyronine (T3), thyroxine (T4), thyroid stimulating hormone (TSH), reverse triiodothyronine (rT3), free thyroxine (FT4), free triiodothyronine (FT3). Weight and height were measured and body mass index (BMI) were calculated (weight (kg)/height2 (m)). Subgroup analysis was done according to body mass index. TSH, T4 and rT3 were correlated with BMI (r = 0.66, p = 0.001 and r = 0.12, p = 0.05 and r = 0.65, p = 0.001, respectively). Adolescent girls with BMI ≥ 25 kg m-2 showed higher serum TSH, T4 and rT 3 than subjects with BMI < 25 kg m-2 (p = 0.001, p = 0.05 and p = 0.001, respectively). Present results showed that, although thyroid function was normal in the studied participants TSH and rT3 were positively correlated to BMI. TSH and rT3 could present a marker of altered energy balance in overweight and obese adolescent girls.]]>Allison, D.B., K.R. Fontaine, J.E. Manson, J. Stevens and T.B. VanItallie,199928215301538Begdade, J.D., E.L. Bierman and D. Porte Jr.,19674615491557Burman, K.D., K.R. Latham, Y.Y. Djuh, R.C. Smallridge and Y.C. Tseng et al.,198051106116Chan, J.L., K. Heist, A.M. DePaoli, J.D. Veldhuis and C.S. Mantzoros,20031114091421Chomard, P., G. Vernhes, N. Autissier and G. Debry,198539371378Chopra, I.J.,19816413361347Diekman, M.J., J.A. Romijn, E. Endert, H. Sauerwein and W.M. Wiersinga,1998810811086Duntas, L., H. Hauner, J. Rosenthal and E.F. Pfeiffer,1991158387Forrest, D.,19945167176Freake, H.C. and J.H. Oppenheimer,199515263291Glueck, C.J., H.L. Taylor, D. Jacobs, J.A. Morrison, R. Beaglehole and O.D. Williams,1980626269Goran, M.I.,200084347362Henry, J.B.,1996Judd, H.L., B.J. Davidson, A.M. Frumar, I.M. Shamonki, L.D. Lagasse and S.C. Ballon,1980136859866Katzeff, H.L. and C. Selgrad,1991261E382E388Kiortis, D.N., I. Durack and G. Turpin,1999158446450Knudsen, N., P. Laurberg, L.B. Rasmussen, I. Bulow, H. Perrild, L. Ovesen and T. Jorgensen,20059040194024Koritschoner, N.P., M. Alvarez-Dolado, S.M. Kurz, M.F. Heikenwaelder and C. Hacker et al.,20012499504Krotkiewski, M.,200024S116S116Lacobellis, G., M.C. Ribaudo, A. Zappaaterreno, C.V. Lannucci and F. Leonetti,200562487491Leibel, R., M. Rosenbaum and J. Hirsch,1995332621628Lellouch, J., H. Tran and J.L. Richard,197321755762Leonhardt, U., U. Ritzel, G. Schafer, W. Becker and G. Ramadori,19981577579Lonnqvist, F., L. Nordfors and M. Schalling,1999245643652Munan, L., A. Kelly, C. PetitClerc and B. Billon,197824772777Naslund, E., I. Andersson, M. Degerblad, P. Kogner, J.G. Kral, S. Rossner and P.M. Hellstrom,2000248229308Niskanen, L., S. Haffner, L. Karhunen, A.K. Turpeinen, H. Miettinen and M.I. Unsitupa,199721309313Papavramidis, S.T., A.C. Zisiadis, M.N. Keramouzis, I.I. Kessissoglou, H.A. Antoniadou and A.P. Aidonopoulos,19955298301Rosenbaum, M., J. Hirsch, E. Murphy and R.L. Leibel,200071114211432Ritz, P., J.F. Dumas, A. Salle, G. Simard, Y. Malthiery and V. Rohmer,200263135139Sari, R., M.K. Balci, H. Altunbas and U. Karayalcin, 200359258262Sesmilo, G., R. Casamitjana, I. Halperin, R. Gomis and E. Vilardell,1998139428430Matzen, L.E. and J. Kventy,198938555561Wu, Z., P. Puigserver, U. Andersson, C. Zhang and G. Adelmant et al.,199998115124Yashkov, Y.I., L.I. Vinnitsky, M.V. Proykova and N.T. Vorobyova,2000104853Zimmermann-Belsing, T., G. Brabant, J.J. Holst and U. Feldt-Ramussen,2003149257271