Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2007.4547.4550MoghimS. H.ChalabiM. AbedA. MogharehRezaeiF. TamizifarH. 1220071024The present study evaluated the subgingival presence of Epstein-Barr virus type 1 (EBV-1) in patients with chronic periodontitis with nested-PCR. Subgingival plaque samples from 61 patients with chronic periodontitis with Probing Depth (PD) >= 6 and 40 healthy controls were collected by sterile curette. DNA was extracted. A nested Polymerase Chain Reaction (PCR) method determined presence of EBV-1. The study included 61 patients (34 women, 27 men; 24-69 years of age; mean 43) and 40 periodontally health controls (22 Women, 18 men, 21-69 years in age; mean 41.35%). EBV type 1 was detected in 37 samples (60.7%) and 1 samples (2.5%) of chronic periodontitis patients and healthy subjects, respectively. This study demonstrated that EBV-1 infection is associated with the activity of chronic periodontitis.]]>Amit, R., A. Morag, Z. Ravid, N. Hochman, J. Ehrlich and Z. Zakay-Rones,199263502506Baelum, V. and F. Scheutz,20022979103Borisch, B., M. Caioni, N. Hurwitz, C. Dommann-Scherrer and B. Odermatt et al.,199355748752Contreras, A. and J. Slots,199611381386Contreras, A., W.A. Falkler, C.O. Enwonwu, E.O. Idigbe and K.O. Savage et al.,199712259265Contreras, A., M. Umeda, C. Chen, I. Bakker, J.L. Morrison and J. Slots,199970478484Contreras, A. and J. Slots,200035316Contreras, A., H. Nowzari and J. Slots,2000151518Ezzo, P.J. and C.W. Cutler,2003322435Haffajee, A.D. and S.S. Socransky,1994578111Idesawa, M., N. Sugano, K. Ikeda, M. Oshikawa, M. Takane, K. Seki and K. Ito,200419230232Imai, S., J. Nishikawa, M. Kuroda and K. Takada,2004258161184Klemenc, P., U. Skaleric, B. Artnik, P. Nograsek and J. Marin,200534147152Konstantinidis, A., D. Sakellari, A. Papa and A. Antoniadis,200540294298Kubar, A., I. Saygun, A. Ozdemir, M. Yapar and J. Slots,20054097104Ling, L.J., C.C. Ho, C.Y. Wu, Y.T. Chen and S.L. Hung,20047514791485Locker, D., G.D. Slade and H. Murray,1998161633Mackowiak, P.A., M. Marling-Cason, J.W. Smith and J.P. Luby,198473987991Moore, W.E. and L.V. Moore,199456677Page, R.C. and J.D. Beck,1997476187Parra, B. and J. Slots,199611289293Salvi, G.E., H.P. Lawrenu, S. Offenbacher and J.D. Beck,199714173201Saygun, I., M. Yapar, A. Ozdemir, A. Kubar and J. Slots,2004198387Saygun, I., A. Kubar, A. Ozdemir and J. Slots,200540187191Slots, J.,2005383362Slots, J., I. Saygun, M. Sabeti and A. Kubar,200641235244Stanford, T.W. and T.D. Rees,200332118135Umeda, M., C. Chen, I. Bakker, A. Contreras, J.L. Morrison and J. Slots,19986911111118Wu, Y.M., L.L. Chen, J. Yan, W.L. Sun and Z.Y. Gu,20058532163220