Pakistan Journal of Biological Sciences1028-88801812-5735Asian Network for Scientific Information10.3923/pjbs.2001.237.240NooraniSaqib Ali M. Zargham Khan Shabbir Ahmad Ghulam Muhammad Hayat Ullah 3200143Male Japanese quails of 7 weeks of age, divided into different equal groups, were fed furazolidone (Fz) at rate of 0(control), 400, 600 mg per kg feed. After four weeks of Fz feeding the birds in all groups were switched to Fz free basal feed for another 4 weeks. A pair-fed (PF) group was maintained and given daily ration as much as consumed by quails of group fed 600 Fz/kg feed. Fz fed quails showed significantly (P<0.05) lower feed consumption, body weights, testes weights, testes volume and diameter of seminiferous tubules than control quails. Microscopically seminiferous tubules of Fz fed quails showed decreased population of germinal epithelial cells, absence of round and elongate spermatids, pyknotic nuclei of round spermatids and round heads of elongate spermatids and young spermatozoa. After cessation of Fz feeding the feed consumption, body weights, testes weights and volume gradually increased and became non-significantly different from those fed 0 mg Fz /kg feed. The microscopic picture of the testes of Fz fed quails also became similar to that of control group. The pair fed group also exhibited significant decrease in body weight, testes weight and volume compared with control. Microscopically the seminiferous tubules had decreased population of germinal epithelial cells, however, no abnormal morphology of spermatids was observed. After increase in feed consumption all parameters of pair-fed group became non-significant from control group earlier than Fz fed groups. This observation suggested that Fz induced decreased intake was not the sole cause of changes in testes of Fz fed quails.]]>Ali, B.H. and A.L. Bartlet,198267437448Andrabi, S.M., M.M. Ahmad and M. Shahab,1998Gallus domesticus).]]>40321325Arbid, M.S., M.M. El-Habbak and M.S.F. Hanafy,199038271279Dixon, R.J., G.G. Arzey and P.J. Nicholls,1992Coturnix coturnix japonica) fed diets containing furazolidone.]]>33835845Gehlaut, B.S., N.S. Mangle and I.C. Datta,198943609612Hernandez-Jauregui P., C. Ravilla-Monsalve and E. Velasco-Monterrubio,19831418Hernandez-Jauregui P., C. Revilla-Monsalve and J. Herrera,19852240247Khan, M.Z., Q. Zaman and N. Islam,199537314318Ludewig, T., G. Gutte and H. Zimmermann,199524712Satoru, K., K. Tetsuo and F. Hiroshi,1977743038Siddique, M., M.Z. Khan and G. Muhammad,199638413417Ullah, H., M.Z. Khan and G. Muhammad,1998Coturnix coturnix japonica): Pathomorphological changes in reproductive tract and reversibility of the induced changes.]]>40212215Webb, D.M. and J.F. Van Vleet,199034693700Zamora Quesada, M.A., L. Paacsh Martinez and R.M. Paramo Ramirez,198617165170Zermeno-Hernandez, A. and L. Paasch Martinnez,198415263266