International Journal of Cancer Research1811-97271811-9735Academic Journals Inc.10.3923/ijcr.2011.125.134Phaseolus vulgaris in DMBA-Induced Sprague-Dawley Rat Mammary Carcinomas]]>PereiraP.C. VicenteA.F. MesquitaM.F. CabritaA.S. 2201172The present study intended to study the influence of Phaseolus vulgaris beans in mammary carcinogenesis especially considering the main malignancy indicators through a histopathology study. A total of 72 female rats 50 days old were divided in three groups and hold in constant conditions temperature, light and humidity. Group B and C received 20 mg of 7, 12 dimethyl benzanthracene by gavages. All the animals were fed with the same standard food, group C were supplemented with Phaseolus vulgaris beans. The study had last for 150 days. Tumors in group C animals had lower pattern grades and lower mitotic counts despite the higher weight gain in this group. These results suggest a protective role of bean consumption in mammary carcinogenesis possibly due to fiber and oligossacharides content, especially present in Phaseolus vulgaris from padrão tarrestre species.]]>Acar, Z., I. Ayan and C. Gulser,2001413121315Aguilera, Y., M.A. Martin-Cabrejas, V. Benitez, E. Mollaa, F.J. Lopez-Andreua and R.M. Estebana,200922678683Ahn, J., A. Schatzkin, J.V. Jr. Lacey, D. Albanes and R. Ballard-Barbash et al.,200716720912102Aune, D., E. De Stefani, A. Ronco, P. Boffetta, H. Deneo-Pellegrini, G. Acosta and M. Mendilaharsu,20092016051615Beylot, M.,200593163168Boyle, P. and P. Boffetta,200911S3S3Bradshaw, P.T., S.K. Sagiv, G.C. Kabat, J.A. Satia and J.A. Britton et al.,20092015091515Caroline, J., M.S. Gross and D.M. Spillman, 2003615641573Cebrian, A., P.D. Pharoah, S. Ahmed, S. Ropero and M.F. Fraga et al.,20062716611669Cho, E., W.Y Chen, D.J. Hunter, M.J. Stampfer, G.A. Colditz, S.E. Hankinson and W.C. Willett,200616622532259Costa, I., R. Moral, M. Solanas and E. Escrich,20043225235Costa, I., M. Solanas and E. Escrich,2002126915927Davis, D.R, M.D. Epp and H.D. Riordan,200423669682Ellison, R.C., Y. Zhang, C.E. McLennan and K.J. Rothman,2001154740747Elston, C.W. and I.O. Ellis,199119403410Fagerland, M.W. and L. Sandvik,20092814871497Ferrucci, L.M., A.J. Cross, B.I. Graubard, L.A. Brinton and C.A. McCarty et al.,2009101178184Foster-Powell, K., S.H.A. Holt and J.C. Brand-Miller,200276556Gago-Dominguez, M., J.M. Yuan, C.L. Sun, H.P. Lee and M.C. Yu,20038916861692Gandini, S., H. Merzenich, C. Robertson and P. Boyle,200036636646Garcia-Segovia, P., A. Sanchez-Villegas, J. Doreste, F. Santana and L. Serra-Majem,20069163167Gaudet, M.M., J.A. Britton, G.C. Kabat, S. Steck-Scott and S.M. Eng et al.,20041314851494Hamer, H.M., D. Jonkers, K. Venema, S. Vanhoutvin, F.J. Troost and R.J. Brummer,200827104119Hara, H., S. Haga, Y. Aoyama and S. Kiriyama,1999129942948Hinnebusch, B.F., S. Meng, J.T. Wu, S.Y. Archer and R.A. Hodin,200213210121017Huang, Z., S.E. Hankinson, G.A. Colditz, M.J. Stampfer and D.J. Hunter et al.,199727814071411Jemal, A., R. Siegel, J. Xu and E. Ward,201060277300Kim, J., S.Y. Lim, A. Shin, M.K. Sung and J. Ro et al.,20099216216Kumar, N., L. Titus-Ernstoff, P. Newcomb, A. Trentham-Dietz, G. Anic and K.M. Egan,200918341345La Vecchia, C., A. Altieri and A. Tavani,200140261267Lopez-Miranda, J., F. Perez-Jimenez, E. Ros, R. De Caterina and L. Badimon et al.,201020284294Makarian, F., M.A. Ramezani, L. Ansari and S. Makarian,20073157161Mathers, J.C.,200288S273S279Michels, K.B., A.P. Mohllajee, E. Roset-Bahmanyar, G.P. Beehler and K.B. Moysich,200710927122749Montazeri, A., J. Sadighi, F. Farzadi, F. Maftoon and M. Vahdaninia et al.,20088278278Moore, M.A., C.B. Park and H. Tsuda,199827229242Moorman, P.G. and P.D. Terry,200480514Owiredu, W.K.B.A., S. Donkor, B.W. Addai and N. Amidu,200912332338Park, Y., L.A. Brinton, A.F. Subar, A. Hollenbeck and A. Schatzkin,200990664671Pierce, J.P., L. Natarajan, B.J. Caan, B.A. Parker and E.R. Greenberg et al.,2007298289298Ronco, A.L., E. De Stefani and R. Dattoli,200211457463Russo, J. and I.H. Russo,20005187200Scharlau, D., A. Borowicki, N. Habermann, T. Hofmann and S. Klenow et al.,20096823953Sun, C.L., J.M. Yuan, W.P. Koh and M.C. Yu,20062713101315Tavani, A., L. Giordano, S. Gallus, R. Talamini and S. Franceschi et al.,200617341345Taylor, E.F., V.J. Burley, D.C. Greenwood and J.E. Cade,20079611391146Terry, P., P. Susuki, F.B. Hu and A. Wolk,20011012811285Terry, P.D., T.E. Rohan and A. Wolk,200377532543Tjonneland, A., J. Christensen, A. Olsen, C. Stripp and B. Thomsen et al.,200718361373Tubiello, F.N., J.F. Soussana and S.M. Howden,20071041968619690Vatten, L.J. and O.P. Foss,19905023412346Wang, N., D.W. Hatcher, R.T. Tyler, R. Toews and E.J. Gawalko,2010Phaseolus vulgaris L.) and chickpeas (Cicer arietinum L.).]]>43589594Willett, W.C.,2001249395411Wu, A.H., M.C. Yu, C.C. Tseng, J. Hankin and M.C. Pike,2003106574579Wu, J.T., S.Y. Archer, B. Hinnebusch, S. Meng and R.A. Hodin,2001280G482G490Zhang, C.X., S.C. Ho, Y.M. Chen, J.H. Fu, S.Z. Cheng and F.Y. Lin,2009125181188Zhang, M., C.D.J. Holman, J.P. Huang and X. Xie,20062810741078