Subscribe Now Subscribe Today
Science Alert Home Journals at Science Alert For Authors For Subscribers Contact Us
 
FOLLOW US:     Facebook    Twitter
   
 
    Publisher: Academic Journals Inc., USA
   
  American Journal of Biochemistry and Molecular Biology is a peer-reviewed international journal dedicated to provide an active forum to the global scientific community for publishing and disseminating high quality research work in the field of biochemistry and molecular biology. Scope of the journal includes: General biochemistry, pathobiochemistry, molecular and cellular biology, molecular medicine, experimental methodologies and the diagnosis, therapy and monitoring of human disease, Host pathogen interaction, molecular detection of pathogen, current advancements in diagnostic techniques, structure, function, and regulation of biologically active molecules, cell signalling, cell cycle, gene structure and expression, gene editing, biochemical mechanisms, protein biosynthesis, protein folding and protein modelling.
  Editor-in-Chief:  Ashok K. Munjal
 
 
Altenburg, J.D. and R.A. Siddiqui, 2009. Omega-3 polyunsaturated fatty acids down-modulate CXCR4 expression and function in MDA-MB-231 breast cancer cells. Mol. Cancer Res., 7: 1013-1020.
PubMed  |  
Altenburg, J.D. and R.A. Siddiqui, 2010. Docosahexaenoic acid downregulates interferon gamma-induced expression of CXCL16 in human aortic smooth muscle cells. Biochem. Biophys. Res. Commun., 391: 609-614.
PubMed  |  
Altenburg, J.D. and R.A. Siddiqui, 2011. The Beneficial Effects of Nutritional Compounds on Breast Cancer Metastasis. In: Breast Cancer: Current and Alternative Therapeutics Modalities, Gunduz, E. (Eds.). InTech Open Access Publisher, Rijeka Croatia, pp: 295.
Altenburg, J.D., A.A. Bieberich, C. Terry, K.A. Harvey and J.F. Vanhorn et al., 2011. A synergistic antiproliferation effect of curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: Unique signaling not explained by the effects of either compound alone. BMC-Cancer, 11: 149-149.
PubMed  |  
Altenburg, J.D., K.A. Harvey, S. McCray, Z. Xu and R.A. Siddiqui, 2011. A novel 2,6-diisopropylphenyl Docosahexaenoamide conjugate induces apoptosis in T cell acute lymphoblastic leukemia cell lines. Biochem. Biophys Res. Communi., 411: 427-432.
PubMed  |  
Amtul, Z., A.U. Rahman, R.A. Siddiqui and M.I. Choudhary, 2002. Chemistry and mechanism of urease inhibition. Curr. Med. Chem., 9: 1323-1348.
CrossRef  |  PubMed  |  Direct Link  |  
Amtul, Z., C. Follmer, S. Mahboob, Atta-Ur-Rahman and M. Mazhar et al., 2007. Germa-gamma-lactones as novel inhibitors of bacterial urease activity. Biochem. Biophys. Res. Commun., 35: 457-463.
CrossRef  |  PubMed  |  
Antalis, C., K.K. Buhman and R.A. Siddiqui, 2007. Differential expression of ACAT-1 and ACAT-2 in mammary epithelial cells at various stages of transformation. Proceedings of the 2nd Annual Symposium on The Role of Dietary Fatty Acids in the Prevention and treatment of Disease, October 24-26, 2007, Winston-Salem, NC., USA -.
Antalis, C.J., A. Uchida, K.K. Buhman and R.A. Siddiqui, 2011. Migration of MDA-MB-231 breast cancer cells depends on the availability of exogenous lipids and cholesterol esterification. Clin. Exp. Metastasis, 28: 733-741.
PubMed  |  
Antalis, C.J., T. Arnold, B. Lee, K.K. Buhman and R.A. Siddiqui, 2009. Docosahexaenoic acid is a substrate for ACAT1 and inhibits cholesteryl ester formation from oleic acid in MCF-10A cells. Prostaglandins Leukotrienes Essential Fatty Acids, 80: 165-171.
PubMed  |  
Antalis, C.J., T. Arnold, T. Rasool, B. Lee, K.K. Buhman and R.A. Siddiqui, 2010. High ACAT1 expression in estrogen receptor negative basal-like breast cancer cells is associated with LDL-induced proliferation. Breast Cancer Res. Treat., 122: 661-670.
PubMed  |  
Bentz, M., K. Harvey, D. Butrschi, D. English and R.A. Siddiqui, 1999. Induction of neutrophil calcium mobilization by phospjatidic acid-enriched plasma membranes. IUBMB-Life, 48: 1-7.
Blair, H.T., S.N. McCutcheon, D.D.S. Mackenzie, J.E. Ormsby, R.A. Siddiqui, P.D. Gluckman and B.H. Breier, 1988. Genetic selection for insulin-like growth factor-1 in growing mice is associated with altered growth. Endocrinology, 123: 1690-1692.
CrossRef  |  
Bush, J., K. Hypes, L. Jenski, R.A. Siddiqui and W. Stillwell, 2004. DHA inhibits TRAIL-mediated apoptosis in H460 human lung cancer cells. Proceedings of the 39th Annual Southeastern Regional Lipid Conference, November 6-8, 2004, Cashiers, NC., USA -.
Bush-O'Donnell, J., R.A. Siddiqui and W. Stillwell, 2006. Trans-fats increase proliferation and membrane complexity in A549 human lung carcinoma cells. Proceedings of the Experimental Biology Meeting, April 1-6, 2006, San Francisco, USA -.
Castillo, A., N. Ruzmetov, K. Harvey, W. Stillwell, G. Zaloga and R. Siddiqui, 2005. Docosahexaenoic acid inhibits protein kinase C translocation/activation and cardiac hypertrophy in rat cardiomyocytes. J. Mol. Gene. Med., 1: 18-25.
Direct Link  |  
Cui, Y., D. English, S. Neel, K. Harvey and R. Siddiqui et al., 1994. Parallel up-regulation of CD11B and CD45 on neutrophilic leukocytes exposed to soluble factors of oral pathogens. Biochem. Mol. Biol. Int., 33: 45-54.
PubMed  |  Direct Link  |  
Cui, Y., D.K. English, R.A. Siddiqui, M. Herenyiova and G.N. Garcia, 1997. Activation of endothelial cell phospholipase D by migrating neutrophils. J. Invest. Med., 45: 388-393.
PubMed  |  
Cui, Y., K. Harvey, L. Akard, J. Jansen, C. Hughes, R.A. Siddiqui and D. English, 1994. Regulation of neutrophil responses by phosphotyrosine phosphatase. J. Immunol., 152: 5420-5428.
Direct Link  |  
Cui, Y., K. Harvey, R.A. Siddiqui, J. Jansen and L. Akard et al., 1996. Cytosolic inactivation of translocated neutrophil plasma membrane protein tyrosine phosphatase. Blood, 87: 341-349.
Direct Link  |  
Dumaual, A., R. Siddiqui and W. Stillwell, 2004. Docosahexaenoic Acid (DHA)-induced lateral phase separation in sphingomyelin-rich, cholesterol-rich planar lipid bilayers as visualized by Atomic Force Microscopy (AFM). Proceedings of the 36th Central Regional Meeting of the American Chemical Society, June 2-4, 2004, Indianapolis, IN., USA -.
English, D., C. Yi, R.A. Siddiqui, C. Patterson, V. Natarajan, D. Brindley and J.G.N. Garcia, 1999. Induction of endothelial monolayer permeability by phosphatidate. J. Cell. Biochem., 75: 105-117.
PubMed  |  Direct Link  |  
English, D., M. Martin, K. Harvey, L.P. Akard and R. Allen et al., 1997. Characterization and purification of neutrophil ecto-phosphatidic acid phosphohydrolase. Biochem. J., 324: 941-950.
Direct Link  |  
English, D., T. Kovala, Z. Welch, K. Harvey, R.A. Siddiqui, D.N. Brindley and J.G.N. Garcia, 1999. Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesis. J. Hematothr. Stem cell Res., 8: 627-634.
PubMed  |  Direct Link  |  
English, D., Y. Cui and R.A. Siddiqui, 1996. Messenger functions of phosphatidic acid. Chem. Phy. Lipids, 80: 117-132.
CrossRef  |  
Friedman, A.N., R. Siddiqui and B.A. Watkins, 2008. Acute rise of omega-3 polyunsaturated fatty acids during hemodialysis treatment. J. Renal Nutr., 18: 301-303.
PubMed  |  
Garcia, J.G.N., A. Verin, K. Schaphosrt, R.A. Siddiqui, C.E. Patterson, C. Csortos and V. Natarajan, 1999. Regulation of endothelial cell myosin light chain kinase by Rho, cortactin and p60src. Am. J. Physiol., 276: L989-L998.
Harvey, K., R.A. Siddiqui and D. English, 1997. Up regulation of CD11b adhesion molecules to neutrophil plasma membranes by phosphatidic acid. ISBBP Symp. Biochem. Biophys., 2: 205-209.
Harvey, K., R.A. Siddiqui, D. Sliva, J.G.N. Garcia and D. English, 2002. Serum factors involved in human microvascular endothelial cell morphogenesis. J. Lab. Clin. Med., 140: 188-198.
CrossRef  |  PubMed  |  
Harvey, K., Y. Cui, L. Akard, J. Jansen, R. Ash, R.A. Siddiqui and D. English, 1994. Cytokine-Stimulated Up-Regulation of Protein Tyrosine Phosphatase in Neutrophils. In: Progress in Clinical and Biological Research, Worthington-Shite, D., A. Gee and S. Gross (Eds.). Wiley-Liss and Co., New York, USA., pp: 257-260.
Harvey, K.A., C. Paranavitana, G. Zaloga and R.A. Siddiqui, 2006. Rho Kinase activation through diverse receptor-mediated pathways regulates fibroblast differentiation and transformation. Proceedings of the Experimental Biology Meeting, April 1-6, 2006, San Francisco, USA -.
Harvey, K.A., C.L. Walker, T.M. Pavlina, Z. Xu, G.P. Zaloga and R.A. Siddiqui, 2010. Long-chain saturated fatty acids induce pro-inflammatory responses and impact endothelial cell growth. Clin. Nutr., 29: 492-500.
CrossRef  |  
Harvey, K.A., C.L. Walker, Z. Xu, P. Whitley and T.M. Pavlina et al., 2010. Oleic acid inhibits stearic acid-induced inhibition of cell growth and pro-inflammatory responses in human aortic endothelial cells. J. Lipid Res., 51: 3470-3480.
Harvey, K.A., C.L. Walker, Z. Xu, P.Whitley and R.A. Siddiqui, 2012. Trans fatty acids: Induction of a pro-inflammatory phenotype in endothelial cells. Lipids, 47: 647-657.
PubMed  |  
Harvey, K.A., C.N. Paranavitana, G.P. Zaloga and R.A. Siddiqui, 2007. Diverse signaling pathways regulate fibroblast differentiation and transformation through Rho kinase activation. J. Cell Physiol., 211: 353-363.
CrossRef  |  PubMed  |  
Harvey, K.A., R.A. Siddiqui, J. Jansen, L.P. Akard and J.M. Thompson et al., 1996. Growth factor induction of cytosolic protein tyrosine kinase activity in human haemopoietic progenitor cells isolated by flow cytometry. Br. J. Haemotol., 93: 515-521.
PubMed  |  
Harvey, K.A., R.A. Siddiqui, M. Reeves, T. Kovala, M. Dugan, P. Akard and D. English, 1999. Characterization and partial purification of CD34+ progenitor cell ecto-phosphatidic acid phosphohydrolase. Biochem. Mol. Biol. Int., 47: 9-23.
Direct Link  |  
Harvey, K.A., T. Arnold, T. Rasool, C. Antalis, S.J. Miller and R.A. Siddiqui, 2008. Trans-fatty acids induce pro-inflammatory responses and endothelial cell dysfunction. Br. J. Nutr., 99: 723-731.
PubMed  |  
Harvey, K.A., Z. Welch, D. Sliva and R.A. Siddiqui, 2010. Role of Rho kinase in sphingosine 1-phosphate-mediated endothelial and smooth muscle cell migration and differentiation. Mol. Cell Biochem., 342: 7-19.
PubMed  |  
Harvey, K.A., Z. Xu, P. Whitley, V.J. Davisson and R.A. Siddiqui, 2010. Characterization of anticancer properties of 2,6-diisopropylphenol-docosahexaenoate and analogues in breast cancer cells. Bioorganic Med. Chem., 18: 1866-1874.
CrossRef  |  
Jackson, K., R.A. Siddiqui and W. Stillwell, 2004. Development and characterization of a novel anticancer agent using a polyunsaturated fatty acid conjugated to a commonly utilized anesthetic. Proceedings of the 39th Annual Southeastern Regional Lipid Conference, November 6-8, 2004, Cashiers, NC., USA -.
Jackson, K., R.A. Siddiqui, S.R. Shaikh, A. Castillo, M. Zeruga and W. Stillwell, 2003. The Mediterranean Diet: A molecular study. Proceedings of the 38th Annual Southeastern Regional Lipid Conference, November 12-14, 2003, Cashiers, North Carolina -.
Jackson, K.R., R. Siddiqui, S.R. Shaikh and W. Stillwell, 2004. Synthesis and characterization of novel fatty acid conjugated anti-cancer agents. Proceedings of the 36th Central Regional Meeting of the American Chemical Society, June 2-4, 2004, Indianapolis, IN., USA -.
Jin, N., R.A. Siddiqui, D. English and R.A. Rhoads, 1996. Communication between tyrosine kinase pathway and myosin light chain kinase pathway in smooth muscle. Am. J. Physiol., 271: H1348-H1355.
Direct Link  |  
Kroonsberg, C., S.N. McCutcheon, R.A. Siddiqui, D.D.S. Mackenzie and H.T. Blair et al., 1989. Reproductive performance and fetal growth in female mice from lines divergently selected on the basis of plasma IGF-1 concentrations. J. Reprod. Fertil., 87: 349-353.
CrossRef  |  
McCutcheon, S.N., H.T. Blair, R.A. Siddiqui, D.D.S. Mackenzie, B.H. Breier and P.D. Gluckman, 1989. Prediction of genetic merit for productivity based on metabolic characteristics during the growth period. Proceedings of the 7th International Conference on Production Disease in Farm Animals, July 25-27, 1989, Cornell University, New York, pp: 38-40.
Mesaik, M.A., K.M. Khan, Z. Ullah, S. Rahat and M.I. Choudhary et al., 2005. Immunomodulatory properties of synthetic imidazolone derivatives. Lett. Drug Design Discovery, 2: 490-496.
CrossRef  |  Direct Link  |  
Mesaik, M.A., Z.U. Haq, A.R. Rahman, M. Yousaf, R.A. Siddiqui, A. Ahmad and M.I. Choudhary, 2006. Biological and molecular docking studies on coagulin-H: Human IL-2 novel natural inhibitor. Proceedings of the 10th International Symposium on Natural Product Chemistry, January 6-9, 2006, Karachi, Pakistan -.
Mesaik, M.A., Zaheer-ul-Haq, S. Murad, Z. Ismail and N.R. Abdullah et al., 2006. Biological and molecular docking studies on coagulin-H: Human IL-2 novel natural inhibitor. Mol. Immunol., 43: 1855-1863.
CrossRef  |  PubMed  |  Direct Link  |  
Minner, D.E., P. Rauch, A.P. Siegel, J. Stelzer and J. Kas et al., 2009. Tuning cellular mechano-response using biomembrane-mimicking substrates of adjustable fluidity. Biophys. J., 96: 521a-521a.
CrossRef  |  
O'Sullivan, U., P.D. Gluckman, B.H. Breier, S. Woodall, R.A. Siddiqui and S.N. McCutcheon, 1989. Insulin-like Growth Factor-1 (IGF-1) in mice reduces weight loss during starvation. Endocrinology, 125: 2793-2794.
CrossRef  |  
Paranavitana, C., K. Harvey and R.A. Siddiqui, 2006. Omega-3 polyunsatureated fatty acids induce apoptosis in breast cancer cells through activation and translocation of neutral sphingomyelinase-2. Proceedings of the Experimental Biology Meeting, April 1-6, 2006, San Francisco, USA -.
Reeves, M.I., R.A. Siddiqui and D. English, 1997. Role of phosphatidic acid in neutrophil cellular signalling. ISBBP Symp. Biochem. Biophys., 2: 147-156.
Rizzo, M.T., S.H. Boswell, R. Siddiqui, C. Carlo-Stella and V. Rizzoli, 1995. Transcriptional activation of c-jun by arachidonic acid is mediated by a protein tyrosine kinase cascade involving activation of c-jun kinase. Proceedings of the 9th International Conference on Second Messengers and Phosphoproteins, October 27-November 1, 1995, Nashville, TN -.
Ruzmetov, N., M. Sosa, N. Courtney and R. Siddiqui, 2006. Anesthesia, mechanical ventilation and related complications in rodents. Adequacy of Anesthesia and Modern Technologies in Intensive Therapy, September 7-9, 2006, Samarkand, Uzbekistan. -.
Shaikh, S.R., A. Dumaual, S.R. Wassall, V. Cherezov, M. Caffrey, R. Siddiqui and W. Stillwell, 2004. Docosahexaenoic and oleic acid differentially phase separate from lipid rafts in model membranes and cells. Proceedings of the 36th Central Regional Meeting of the American Chemical Society, June 2-4, 2004, Indianapolis, IN., USA -.
Shaikh, S.R., A.C. Dumaual, D. LoCascio, R.A. Siddiqui and W. Stillwell, 2003. Acylchain unsaturation in PEs modulates phase separation in from lipid raft molecules. Biochim. Biophys. Res. Comm., 311: 793-796.
CrossRef  |  PubMed  |  
Shaikh, S.R., R. Siddiqui, V. Cherezov, M. Caffrey, D. LoCascio, S.R. Wassall and W. Stillwell, 2004. Polyunsaturation and lipid rafts: Implications for cellular signaling. Proceedings of the Keystone Symposium on Molecular Cell Biology of Lipid Domains, March 26-31, 2004, Vancouver, Canada -.
Shaikh, S.R., R.A. Siddiqui, D. LoCascio, W. Stillwell and S.R. Wassall, 2004. A role for docosahexaenoic acid-containing phosphatidylethanolamine in lipid raft phase separations. Biophys. J., 87: 1752-1766.
CrossRef  |  Direct Link  |  
Shaikh, S.R., R.A. Siddiqui, M. Wu, A. Castillo, S.R. Wassall, A. Dumaual and W. Stillwell, 2003. A role of docosahexaenoic acid in phase separation from lipid rafts: Implications for cellular signaling. Proceedings of the 38th Annual Southeastern Regional Lipid Conference, November 12-14, 2003, Cashiers, North Carolina -.
Shaikh, S.R., R.A. Siddiqui, S. Wassall and W. Stillwell, 2002. Fish oils, membranes and eternal life. Proceedings of the 37th Annual Southeastern Regional Lipid Conference, November 6-8, 2002, Cashiers, North Carolina -.
Siddiqui, R. and D. English, 1995. Neutrophil calcium mobilization is stimulated by phosphatidic acid: A receptor driven process. Proceedings of the 9th International Conference on Second Messengers and Phosphopoteins, October 27-November 1, 1995, Nashville, TN -.
Siddiqui, R., D. Pandya, K. Harvey and G.P. Zaloga, 2006. Nutrition modulation of cachexia/proteolysis. Nutr. Clin. Pract., 21: 155-167.
PubMed  |  
Siddiqui, R., N. Ruzmetov, K. Harvey, T. Arnold, C. Antalis and G. Zaloga, 2007. Trans fatty acids promote Atherosclerosis and sudden Cardiac death in experimental models. Proceedings of the 5th EuroFed Lipid Congress, September 16-19, 2007, Gothenburg, Sweden, USA. -.
Siddiqui, R.A. and D. English, 1996. Phosphatidic acid binding to human neutrophils: Effects on tyrosine kinase-regulated intracellular Ca2+ mobilization. Cell. Signalling, 8: 349-354.
CrossRef  |  
Siddiqui, R.A. and D. English, 1997. Phosphatidic acid elicits calcium mobilization and actin polymerization through a tyrosine kinase-dependent process in human neutrophils: A mechanism for induction of chemotaxis. Biochem. Biophys. Acta (BBA)-Lipids Lipid Metab., 1349: 82-95.
CrossRef  |  
Siddiqui, R.A. and D. English, 2000. Phosphatidylinosityol 3-kinase is involved in phosphatidic acid-induced neutrophil chemotaxis. Biochem. Biophys. Acta, 1483: 161-173.
Siddiqui, R.A. and J.F. Williams, 1987. Interaction of vasopressin and prostaglandin E2 in the development of cancer cachexia. Med. Sci. Res., 15: 45-46.
Siddiqui, R.A. and J.F. Williams, 1989. The regulation of fatty acid and branched-chain amino acid oxidation in cancer cachectic rats: A proposed role for a cytokine, eicosanoid and hormone trilogy. Biochem. Med. Metab. Biol., 42: 71-86.
CrossRef  |  
Siddiqui, R.A. and J.F. Williams, 1990. Tentative identification of the toxohormones of cancer cachexia: Roles of vasopressin, prostaglandin E2 and cachectin-TNF. Biochem. Int., 20: 787-797.
PubMed  |  
Siddiqui, R.A. and J.H. Exton, 1992. Oleate stimulation of diacylglycerol formation from phosphatidylcholine through effects on phospholipase D and phosphatidate phosphohydrolase. Eur. J. Biochem., 210: 601-607.
CrossRef  |  
Siddiqui, R.A. and J.H. Exton, 1992. Phospholipid base exchange activity in rat liver plasma membranes. Evidence for regulation by G-protein and P2y-purinergic receptor. J. Biol. Chem., 267: 5755-5761.
Direct Link  |  
Siddiqui, R.A. and Y.C. Yang, 1995. Interleukin-11 induces phosphatidic Acid formation and activates MAP kinase in mouse 3T3-L1 cells. Cell. Signalling, 7: 247-259.
CrossRef  |  
Siddiqui, R.A., 1980. Effects of drugs on tryptophan-protein binding. M.Sc. Thesis, University of Karachi, Karachi, Pakistan..
Siddiqui, R.A., 1988. An enquiry into the metabolic basis of cancer cachexia using Walker 256 carcinosarcoma. Ph.D. Thesis, Australian National University, Canberra, Australia..
Siddiqui, R.A., C.A. Labarrere and R.J. Kovacs, 2000. Prevention of cardiac hypertrophy with omega 3-fatty acids: Potential cell signaling targets. Curr Org. Chem., 4: 1145-1156.
CrossRef  |  
Siddiqui, R.A., D. Burtschi and R. Kovacs, 2000. Phosphatidic acid induces calcium influx in neutrophils via verapamil-sensitive calcium channels. J. Cellular Biochem., 78: 297-304.
PubMed  |  
Siddiqui, R.A., D. English and J.G.N. Garcia, 1995. Rationale for juxtacrine regulation of neutrophil interactions with the stimulated endothelium. J. Lab. Clin. Med., 125: 18-25.
PubMed  |  Direct Link  |  
Siddiqui, R.A., D. English, Y. Cui, M. Martin and J. Wentland et al., 1995. Phorbol ester-induced priming of superoxide generation by phosphatidic acid-stimulated neutrophils and granule-free neutrophil cytoplasts. J. Leukocyte Biol., 257: 187-194.
PubMed  |  
Siddiqui, R.A., H.T. Blair, S.N. McCutcheon, D.D.S. Mackenzie, P.D. Gluckman and B.H. Breier, 1990. Developmental patterns of plasma insulin-like growth factor-I (IGF-I) and body growth in mice from lines divergently selected on the basis of plasma IGF-I. J. Endocrinol., 124: 151-158.
CrossRef  |  PubMed  |  
Siddiqui, R.A., J. Weisehan, L. Jenski, W. Stillwell and R. Kovacs, 2001. Induction of cell cycle arrest and apoptosis by docosahexaenoic acid in serum in Jurkat cells. Proceedings of the 34th International Congress of Physiological Sciences, August 26-31, 2001, Christchurch, New Zealand -.
Siddiqui, R.A., J.D. Wiesehan, H. Hunter, K. Harvey, G. Zaloga and W. Stillwell, 2002. Docosahexaenoic acid induces cell cycle arrest via hypophosphorylation of human retinoblastoma protein in Jurkat leukemic cells. Proceedings of the 5th Congress of the International Society for the Study of Fatty Acids and Lipids, May 7-11, 2002, Montreal, Canada -.
Siddiqui, R.A., J.D. Wiesehan, M. Slimko, W. Stillwell, L.J. Jenski and R.J. Kovacs, 2001. Phosphatidic acid prevents the cytotoxic effects of docosahexaenoic acid in Jurkat leukemic cells. Proceedings of the 34th International Congress of Physiological Sciences, August 26-31, 2001, Christchurch, New Zealand -.
Siddiqui, R.A., J.G.N. Garcia, M. Martin, J. Wentland, L. Akard, J. Thompson and D. English, 1994. Role of diacylglycerol and phosphatidic acid in superoxide release and protein tyrosine phosphorylation in neutrophils. Proceedings of the 30th National Meeting, Society of Leukocyte Biology, September 21-24, 1994, Tucson, Arizona -.
Siddiqui, R.A., J.H. Darakshan and H.A. Haleem, 1983. Effect of drugs on the distribution of tryptophan in plasma, liver and brain in a desert lizard. Pak. J. Biochem., 16: 1-5.
Siddiqui, R.A., K. Harvey and W. Stillwell, 2008. Anticancer properties of oxidation products of docosahexaenoic acid. Chem. Phys. Lipids, 153: 47-56.
PubMed  |  
Siddiqui, R.A., K. Harvey, T. Arnold, T. Rasool and C. Antalis, 2006. Trans fatty acids induce Pro-inflammatory responses and Endothelial dysfunction. Proceedings of the 46th Annual Meeting of the American Society of Cell Biology, December 9-13, 2006, San Diego, USA. -.
Siddiqui, R.A., K.A. Harvey and G.P. Zaloga, 2008. Modulation of enzymatic activities by n-3 polyunsaturated fatty acids to support cardiovascular health. J. Nutr. Biochem., 19: 417-437.
Direct Link  |  
Siddiqui, R.A., K.A. Harvey, C. Walker and Z. Xu, 2012. Synergistic effects of Docosahexaenoic acid and curcumin in Breast Cancer. Proceedings of the 2012-Hobart Symposium, October 6-7, 2012, Tasmania, Australia, -.
Siddiqui, R.A., K.A. Harvey, D. Herera, N. Patel, C. Paranavitana, W. Stillwell and G. Zaloga, 2006. Docosahexaenoic acid and polyphenols synergistically induce apoptosis in breast cancer cells by activating protein phosphatses. Proceedings of the Experimental Biology Meeting, April 1-6, 2006, San Francisco, USA -.
Siddiqui, R.A., K.A. Harvey, G.P. Zaloga and W. Stillwell, 2007. Modulation of lipid rafts by Ω-3 fatty acids in inflammation and cancer: Implications for use of lipids during nutrition support. Nutr. Clin. Pract., 22: 74-88.
CrossRef  |  PubMed  |  
Siddiqui, R.A., K.A. Harvey, N. Ruzmetov, S.J. Miller and G.P. Zaloga, 2009. Omega-3 fatty acids prevent whereas Trans fatty acids induce vascular inflammation and sudden cardiac death. Br. J. Nutr., 102: 1811-1819.
CrossRef  |  PubMed  |  Direct Link  |  
Siddiqui, R.A., K.A. Harvey, S.J. Miller and G.P. Zaloga, 2008. Impact of omega-3 and trans fatty acids on vascular remodeling: Opposing roles in cardiovascular health. Curr. Enzyme Inhib., 4: 60-72.
CrossRef  |  
Siddiqui, R.A., L. Jenski, K. Neff., K. Harvey, R.J. Kovacs and W. Stillwell, 2001. Docosahexaenoic acid induces apoptosis in Jurkat cells by a protein phosphatase-mediated process. Biochem Biophys Acta, 1499: 265-275.
CrossRef  |  
Siddiqui, R.A., L.J. Jenski, J.D. Wiesehan, M.V. Hunter, R.J. Kovacs and W. Stillwell, 2001. Prevention of docosahexaenoic acid-induced cytotoxicity by phosphatidic acid in Jurkat leukemic cells: the role of protein phosphatase-1. Biochem. Biophys. Acta., 1541: 188-200.
PubMed  |  
Siddiqui, R.A., L.J. Jenski, K. Harvey, J. Wiesehan, W. Stillwell and G. Zaloga, 2003. Cell cycle arrest in Jurkat leukemic cells: A possible role for dososahexaenoic acid. Biochem. J., 371: 621-629.
CrossRef  |  Direct Link  |  
Siddiqui, R.A., L.J. Jenski, K.A. Harvey, J.D. Weisehan, W. Stillwell and G.P. Zaloga, 2002. Docosahexaenoic acid induces cell cycle arrest by inhibiting phosphorylation of retinoblastoma protein in Jurkat leukemic cells. Proceedings of the 37th Annual Southeastern Regional Lipid Conference, November 6-8, 2002, Cashiers, North Carolina -.
Siddiqui, R.A., L.P. Akard, J.G.N. Garcia, Y. Cui and D. English, 1999. Chemotactic migration triggers interleukin-8 generation in neutrophilic leukocytes. J. Immunol., 162: 1077-1083.
Siddiqui, R.A., M. Hunter, G. Zaloga and W. Stillwell, 2002. Docosahexaenoic acid prevents phenylephrine-induced cardiac hypertrophy through Ras-Raf-MAP kinase pathway. Proceedings of the 5th Congress of the International Society for the Study of Fatty Acids and Lipids, May 7-11, 2002, Montreal, Canada -.
Siddiqui, R.A., M. Zerouga, M. Wu, A. Castillo, G.P. Zaloga and W. Stillwell, 2004. Novel conjugates, docosahexaenoyl-Propofol and eicosapentaenoyl (EPA)-Propofol, inhibit metastasis and induce apoptosis in breast cancer cells. Proceedings of the Annual Meeting of the 95th American Association for Cancer Research, March 27-31, 2004, Orlando, Florida, pp: 884-884.
Siddiqui, R.A., M. Zerouga, M. Wu, A. Castillo, K. Harvey, G.P. Zaloga and W. Stillwell, 2005. Anticancer properties of propofol-docosahexaenoate and propofol-eicosapentaenoate on breast cancer cells. Breast Cancer Res., 7: R645-R645.
CrossRef  |  
Siddiqui, R.A., N. Ruzmetov, K. Harvey, T. Arnold, S. Hassan, T. Rasool and C. Antalis, 2007. Trans fatty acids promote Atherosclerotic lesions and induce sudden Cardiac death. Proceedings of the 47th Annual Conference on cardiovascular diseases, February 28-March 3,2007, American heart Association, Orlando, Florida. -.
Siddiqui, R.A., N. Ruzmetov, K.A. Harvey, M. Zerouga and C. Terry et al., 2005. Omega-3 fatty acids inhibit PKA and CaMKII activities and improve survival following myocardial infarction. Proceedings of the 2nd Annual Symposium of America Heart association-Targeting Heart Failure: New Science, New Tools, New Strategies, July 24-27, 2005, Keystone, Colorado -.
Siddiqui, R.A., N. Ruzmetov, K.A. Harvey, W. Stillwell and G. Zaloga, 2006. Omega-3 polyunsaturated fatty acids improve survival following myocardial infarction and inhibit phenylephrine-induced hypertrophy by regulating protein kinase activities. Proceedings of the Experimental Biology Meeting, April 1-6, 2006, San Francisco, USA -.
Siddiqui, R.A., S. Hassan, K. Harvey, T. Das, P. Mukerji and S. DeMichele, 2007. Attenuation of muscle loss and proteolysis by curcumin C3 complex in MAC-16 tumor-bearing mice. Proceedings of the 4th Cachexia Conference, December 5-9, 2007, Tampa, FL., USA -.
Siddiqui, R.A., S. Hassan, K. Harvey, T. Das, P. Mukerji and S. DeMichele, 2009. Attenuation of cancer cachexia by curcumin C3 complex in MAC-16 tumor-bearing mice. Br. J. Nutr., 102: 967-975.
CrossRef  |  PubMed  |  Direct Link  |  
Siddiqui, R.A., S.N. McCutcheon, D.D.S. Mackenzie, H.T. Blair, J.E. Ormsby, P.D. Gluckman and B.H. Breier, 1989. Role of testosterone in regulating the growth of mice from lines selected for low vs high plasma insulin-like growth factor-I concentrations. Acta Endocrinol., 121: 686-690.
CrossRef  |  
Siddiqui, R.A., S.N. McCutcheon, H.T. Blair, D.D. Mackenzie, P.C. Morel, B.H. Breier and P.D. Gluckman, 1992. Growth allometry of organs, muscles and bones in mice from lines divergently selected on the basis of plasma insulin-like growth factor-I. Growth Dev. Aging., 56: 53-60.
PubMed  |  Direct Link  |  
Siddiqui, R.A., S.R. Shaikh, L.A. Sech, H.R. Yount, W. Stillwell and G.P. Zaloga, 2004. Omega 3- fatty acids: Health benefits and cellular mechanism of action. Mini-Rev. Med. Chem., 4: 859-871.
PubMed  |  
Siddiqui, R.A., S.R. Shaikh, R. Kovacs, W. Stillwell and G. Zaloga, 2004. Inhibition of phenylephrine-induced cardiac hypertrophy by docosahexaenoic acid. Proceedings of the 6th Congress of the International Society for the Study of Fatty Acids and Lipids, June 27-July 1, 2004, Brighton, UK -.
Siddiqui, R.A., S.R. Shaikh, W. Stillwell and G.P. Zaloga, 2004. Inhibition of phenylephrin-induced cardiac hypertrophy by docosahexaenoic acid. J. Cell. Biochem., 92: 1141-1159.
CrossRef  |  
Siddiqui, RA., K.A. Harvey, Z. Xu, E.M. Bammerlin, C. Walker and J.D. Altenburg, 2011. Docosahexaenoic acid: A natural powerful adjuvant that improves efficacy for anticancer treatment with no adverse effects. BioFactors, 37: 399-412.
CrossRef  |  
Siddiqui, RA., N. Ruzmetov, K. Harvey, W. Stillwell and G. Zaloga, 2006. Omega-3 polyunsaturated fatty acids inprove survival following myocardial infarction and inhibit phenylephrine-induced hypertrophy by regulating protein kinase activities. Proceedings of the 10th International Symposium on Natural Product Chemistry, January 6-9, 2006, Karachi, Pakistan -.
Slivova, V., G. Zaloga, S.J. DeMichele, P. Mukerji and Y.S. Huang et al., 2005. Green tea polyphenols modulate secretion of urokinase plasminogen activator (uPA) and inhibit invasive behavior of breast cancer cells. Nutr. Cancer, 51: 66-73.
PubMed  |  
Song, A., X.L. Xia, R.A. Siddiqui and M.A. Harrington, 1998. PLA2-independent induction of CSF-1 gene expression in growth-arrested fibroblasts. Int. J. Hematol., 67: 249-256.
PubMed  |  Direct Link  |  
Stillwell, W., S.R. Shaikh, D. Lo Cascio, R.A. Siddiqui, J. Seo, R.S. Chapkin and S.R. Wassall, 2006. Docosahexaenoic Acid: An Important Membrane-Altering Omega-3 Fatty Acid. In: Frontiers in Nutrition Research, Huamg, J.D. (Ed.). Chapter 8. NOVA Science Publishers, New York, USA., pp: 249-271.
Stillwell, W., S.R. Shaikh, M. Zerouga, R.A. Siddiqui and S.R. Wassall, 2005. Docosahexaenoic acid affects cell signaling by altering lipid rafts. Rep. Nutr. Dev., 45: 559-579.
CrossRef  |  
VanHorn, F., J.D. Altenburg, K.A. Harvey, Z. Xu, R.J. Kovacs and R.A. Siddiqui, 2012. Attenuation of niacin-induced prostaglandin D2 generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells. J. Inflammat. Res., 5: 37-50.
CrossRef  |  
Vasquez, C., R.A. Siddiqui, A.P. Moreno and E.J. Berbari, 2002. A fibroblast-myocyte odel which accounts for slow conductance and fractionated electrogram in Infarct border zones. Comput. Cardiol., 29: 245-248.
Direct Link  |  
Wassall, S.R., S.R. Shaikh, M.R. Brzustowicz, V. Cherezov, R.A. Siddiqui, M. Caffrey and W. Stillwell, 2005. Interaction of polyunsaturated fatty acids with cholesterol: A role in lipid raft phase separation. Macromol. Symp., 219: 73-84.
CrossRef  |  
Williams, J.F. and R.A. Siddiqui, 1989. Cancer cachexia: A hypothesis revisited and a proposal for treatment. Cancer Forum, 13: 87-97.
Williams, J.F. and R.A. Siddiqui, 1990. Biochemistry of cancer cachexia: Review of results, a new hypothesis and a proposal for treatment. Med. Sci. Res., 18: 3-10.
Wu, M., K.A. Harvey, N. Ruzmetov, Z. Welch and L. Sech et al., 2005. Omega-3 polyunsaturated fatty acids attenuate breast cancer growth through activation of aneutral sphingomyelinase-mediated pathway. Int. J. Cancer, 117: 340-348.
PubMed  |  
Xio, H., R.A. Siddiqui, M.A. Al-Hassani, D. Sliva and R.J. Kovacs, 2001. Phospholipids released from activated platelets improve platelet aggregation and endothelial cell migration. Platelets, 12: 163-170.
PubMed  |  
Xu, X., K.A. Harvey, T. Pavlina, G. Dutot and M. Hise et al., 2012. Steroidal compounds in commercial parenteral lipid emulsions. Nutrients, 4: 904-921.
CrossRef  |  
Xu, Z., K. Harvey, T. Pavlina, G. Dutot, G. Zaloga and R. Siddiqui, 2010. An improved method for determining medium-and long-chain FAMEs using gas chromatography. Lipids, 45: 199-208.
CrossRef  |  PubMed  |  
Zaloga, G., K. Harvey, W. Stillwell and R. Siddiqui, 2006. Trans fatty acids and coronary heart disease. Nutr. Clin. Pract., 21: 505-512.
CrossRef  |  
Zaloga, G.P. and R.A. Siddiqui, 2004. Biologically active detary peptides. Mini-Rev. Med. Chem., 4: 815-821.
PubMed  |  
Zaloga, G.P. and R.A. Siddiqui, 2006. A soluble ATP-dependent proteolytic system is responsible for protein degradation. Nutr. Clin. Prac., 21: 88-91.
CrossRef  |  
Zaloga, G.P., K.A. Harvey, W. Stillwell and R. Siddiqui, 2006. Trans fatty acids and coronary heart disease. Nutr. Clin. Pract., 21: 505-512.
Direct Link  |  
Zaloga, G.P., N. Ruzmetov, K.A. Harvey, C. Terry, N. Patel, W Stillwell and R. Siddiqui, 2006. (N-3) long-chain polyunsaturated fatty acids prolong survival following myocardial infarction in rats. J. Nutr., 136: 1874-1878.
PubMed  |  
Zaloga, G.P., R. Siddiqui, C. Terry and P.E. Marik, 2004. Arginine: Mediator or modulator of sepsis? Nutr. Clin. Pract., 19: 201-215.
CrossRef  |  PubMed  |  
Zhang, Y., R.A. Siddiqui, G.P. Zaloga, D.A. Ingram and J. Rehman, 2006. Modulation of endothelial progenitor cells by polyunsaturated omega-3 fatty acids. Proceedings of the Experimental Biology Meeting, April 1-6, 2006, San Francisco, USA -.
Zieger, M.A.J., M. Gupta and R.A. Siddiqui, 2006. Endothelial cell fatty acid unsaturation mediates cold-induced oxidative stress. J. Cell Biochem., 99: 784-796.
PubMed  |  Direct Link  |  

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 

                 home       |       journals        |       for authors       |       for subscribers       |       asci
          © Science Alert. All Rights Reserved