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    Publisher: Asian Network for Scientific Information
   
  Pakistan Journal of Biological Sciences (PJBS) is an international, peer-reviewed and well indexed scientific journal seeks to promote and disseminate the knowledge of biological sciences by publishing outstanding research in the field. Scope of the journal includes: Cell biology, developmental biology, structural biology, microbiology, entomology, toxicology, molecular biology & genetics, biochemistry, biotechnology, biodiversity, ecology, marine biology, plant biology and bioinformatics.

Submit your best paper to PJBS via online submission system.
  Editor-in-Chief:  Hakan UlUKAN
 
 
Ahmad, N., I. Ahmad, S. Umar, Z. Iqbal, M. Samim and F.J. Ahmad, 2014. PNIPAM nanoparticles for targeted and enhanced nose-to-brain delivery of curcuminoids: UPLC/ESI-Q-ToF-MS/MS-based pharmacokinetics and pharmacodynamic evaluation in cerebral ischemia model. Drug Delivery, (In Press). 10.3109/10717544.2014.941076.
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Ahmad, N., S. Umar, M. Ashafaq, M. Akhtar, Z. Iqbal, M. Samim and F.J. Ahmad, 2013. A comparative study of PNIPAM nanoparticles of curcumin, demethoxycurcumin and bisdemethoxycurcumin and their effects on oxidative stress markers in experimental stroke. Protoplasma, 250: 1327-1338.
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Asif, M., S. Umar and H.A. Khan, 2012. Trigonella foenum graecum mitigates proteases and restores antioxidant balance in collagen induced arthritis in rats. Int. J. Pharmaceut. Res., 4: 104-109.
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Aslam, M., S.T. Ahmad, R. Dayal, K. Javid and S. Umar et al., 2012. Nephroprotective action of Peucedanum grande against cadmium chloride induced renal toxicity in Wistar rats. EXCLI J., 11: 444-452.
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Bhat, J.U., N. Qudsia, A. Asia, A.P. Shabir and S.T. Ahmad et al., 2012. Anticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino mice. EXCLI J., 11: 1-6.
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Boddu, S.H., H. Alsaab, S. Umar, S.P. Bonam, H. Gupta and S. Ahmed, 2015. Anti-inflammatory effects of a novel ricinoleic acid poloxamer gel system for transdermal delivery. Int. J. Pharmaceut., 479: 207-211.
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Haider, S., M.S. Alam, H. Hamid, A. Dhulap and S. Umar et al., 2014. Design, synthesis and docking studies of 2-benzoxazolinone-based 1, 2, 4-triazoles as proinflammatory cytokine inhibitors. Med. Chem. Res., 23: 4250-4268.
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Haider, S., M.S. Alam, H. Hamid, S. Shafi and A. Dhulap et al., 2014. Synthesis of novel 2-mercaptobenzoxazole based 1, 2, 3-triazoles as inhibitors of proinflammatory cytokines and suppressors of COX-2 gene expression. Eur. J. Med. Chem., 81: 204-217.
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Hayat, F., A. Salahuddin, S. Umar and A. Azam, 2010. Synthesis, characterization, antiamoebic activity and cytotoxicity of novel series of pyrazoline derivatives bearing quinoline tail. Eur. J. Med. Chem., 45: 4669-4675.
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Khan, Y.A., S. Umar and S.M. Abidi, 2015. Somatic antigens of tropical liver flukes ameliorate collagen-induced arthritis in Wistar rats. PLoS ONE, Vol. 10. 10.1371/journal.pone.0126429.
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Rathore, A., R. Sudhakar, M.J. Ahsan, A. Ali and N. Subbarao et al., 2017. In vivo anti-inflammatory activity and docking study of newly synthesized benzimidazole derivatives bearing oxadiazole and morpholine rings. Bioorg. Chem., 70: 107-117.
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Sajad, M., J. Zargan, J. Sharma, R. Chawla, R. Arora, S. Umar and H.A. Khan, 2011. Increased spontaneous apoptosis of rat primary neurospheres in vitro after experimental autoimmune encephalomyelitis. Neurochem. Res., 36: 1017-1026.
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Sajad, M., J. Zargan, M.A. Zargar, J. Sharma, S. Umar, R. Arora and H.A. Khan, 2013. Quercetin prevents protein nitration and glycolytic block of proliferation in hydrogen peroxide insulted cultured Neuronal Precursor Cells (NPCs): Implications on CNS regeneration. Neurotoxicology, 36: 24-33.
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Sajad, M., J. Zargan, R. Chawla, S. Umar and H.A. Khan, 2011. Upregulation of CSPG3 accompanies neuronal progenitor proliferation and migration in EAE. J. Mol. Neurosci., 43: 531-540.
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Sajad, M., J. Zargan, R. Chawla, S. Umar, M. Sadaqat and H.A. Khan, 2009. Hippocampal neurodegeneration in Experimental Autoimmune Encephalomyelitis (EAE): potential role of inflammation activated myeloperoxidase. Mol. Cell. Biochem., 328: 183-188.
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Sajad, M., M. Asif, S. Umar, J. Zargan and M. Rizwan et al., 2010. Amelioration of inflammation induced oxidative stress and tissue damage by aqueous methanolic extract of Nigella sativa Linn. in arthritic rats. J. Complement. Integr. Med., Vol. 7, No. 1. 10.2202/1553-3840.1454.
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Sajad, M., R. Chawla, J. Zargan, S. Umar, M. Sadaqat and H.A. Khan, 2010. Cytokinetics of adult rat SVZ after EAE. Brain Res., 31: 140-149.
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Singh, A.K., S. Umar, S. Riegsecker, M. Chourasia and S. Ahmed, 2016. Regulation of transforming growth factor β-activated kinase activation by epigallocatechin-3-gallate in rheumatoid arthritis synovial fibroblasts: Suppression of K63-linked autoubiquitination of tumor necrosis factor receptor-associated factor 6. Arthritis Rheumatol., 68: 347-358.
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Tantray, M.A., I. Khan, H. Hamid, M.S. Alam and S. Umar et al., 2016. Synthesis of novel oxazolo[4,5-b]pyridine-2-one based 1,2,3-triazoles as glycogen synthase kinase-3β inhibitors with anti-inflammatory potential. Chem. Biol. Drug Des., 87: 918-926.
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Umar, S., A. Kumar, M. Sajad, J. Zargan and M.M. Ansari et al., 2013. Hesperidin inhibits collagen-induced arthritis possibly through suppression of free radical load and reduction in neutrophil activation and infiltration. Rheumatol. Int., 33: 657-663.
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Umar, S., A.H.M.G. Sarwar, K. Umar, N. Ahmad and M. Sajad et al., 2013. Piperine ameliorates oxidative stress, inflammation and histological outcome in collagen induced arthritis. Cell. Immunol., 284: 51-59.
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Umar, S., A.M. Tyagi, A.K. Singh and A. Haseeb, 2017. Molecular mechanism of rheumatic diseases and efficacy of current therapies. BioMed Res. Int. 10.1155/2017/2401329.
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Umar, S., J. Zargan, K. Umar, S. Ahmad, C.K. Katiyar and H.A. Khan, 2012. Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats. Chemico-Biol. Interact., 197: 40-46.
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Umar, S., K. Umar, A.H.M.G. Sarwar, A. Khan and N. Ahmad et al., 2014. Boswellia serrata extract attenuates inflammatory mediators and oxidative stress in collagen induced arthritis. Phytomedicine, 21: 847-856.
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Umar, S., M. Asif, M. Sajad, M.M. Ansari and U. Hussain et al., 2012. Anti-inflammatory and antioxidant activity of Trachyspermum ammi seeds in collagen induced arthritis in rats. Int. J. Drug Dev. Res., 4: 210-219.
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Umar, S., N.K. Mishra, K. Pal, M. Sajad and M.M. Ansari et al., 2012. Protective effect of rutin in attenuation of collagen-induced arthritis in Wistar rat by inhibiting inflammation and oxidative stress. Indian J. Rheumatol., 7: 191-198.
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Umar, S., O. Hedaya, A.K. Singh and S. Ahmed, 2015. Thymoquinone inhibits TNF-α-induced inflammation and cell adhesion in rheumatoid arthritis synovial fibroblasts by ASK1 regulation. Toxicol. Applied Pharmacol., 287: 299-305.
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Zargan, J., M. Sajad, S. Umar, M. Naime, S. Ali and H.A. Khan, 2011. Scorpion (Odontobuthus doriae) venom induces apoptosis and inhibits DNA synthesis in human neuroblastoma cells. Mol. Cell Biochem., 348: 173-181.
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Zargan, J., M. Sajad, S. Umar, M. Naime, S. Ali and H.A. Khan, 2011. Scorpion (Androctonus crassicauda) venom limits growth of transformed cells (SH-SY5Y and MCF-7) by cytotoxicity and cell cycle arrest. Exp. Mol. Pathol., 91: 447-454.
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Zargan, J., S. Umar, M. Sajad, M. Naime, S. Ali and H.A. Khan, 2011. Scorpion venom (Odontobuthus doriae) induces apoptosis by depolarization of mitochondria and reduces S-phase population in human breast cancer cells (MCF-7). Toxicol. In vitro, 25 : 1748-1756.
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