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| Articles
by
Mohammad Ashraf |
Total Records (
3 ) for
Mohammad Ashraf |
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Mohammad Ashraf
,
Faiz-ul-Hassan Nasim
and
Mohammad Munir Hussain
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Changes in Na+, K+ and inorganic phosphate (Pi) have been quantified in the leachates during early hours of imbibition of untreated and 2, 6, 16 and 24 hours of water pre-treated wheat seeds at 16±1°C. During the course of 24 hours imbibition of untreated seeds, Na+ effluxed 1.2 ppm/seed. K+ concentration at zero hour observed was 2.27 ppm/seed which increased to 7.2±0.9 ppm/seed in leachates of 24 hours of imbibition of control seeds. Rate of K+ leakage from the seed was faster (4.54 ppm/seed/hour) during the initial 30 minutes which decreased to 0.3 ppm/seed/hour at 24 hours of imbibition. Pi leakage remained upto 8.1±1.2 ppm/seed during 24 hours of imbibition in control seeds. When seeds were pretreated in water for 2, 6, 16 and 24 hours, air-dried for a week to their original weights and allowed to re-imbibe for 1-3 days, decrease in ionic concentrations were noticed in their leachates with increase in duration to pre-treatment and least ionic concentrations were noticed in leachates of 24 hour pre-treated seeds. The significance of these changes during early hours of imbibition is discussed. |
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Muhammad Khan Sarfraz
,
Nisar -ur-Rehman
,
Saeed Ahmed
,
Mohammad Ashraf
and
Sabeeh Mohsin
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The present study was conducted to develop sustained release matrix tablets of naproxen with the help of a hydrophobic polymer, Ethyl Cellulose (EC). Matrix tablets were prepared by incorporating various proportions of EC in the matrix system using wet granulation technique. The rate of drug release from the matrix tablets was found to be very slow and could not produce the desired release profiles in 12 h testing time. However, the tablets prepared by slightly modifying the wet granulation method exhibited comparatively linear and desirable release rate. No significant difference in the release profiles of naproxen matrix tablets was observed at different stirring speeds and storage conditions. |
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Izzat Yasmin
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Mohammad Ashraf
and
Faiz-ul-Hassan Nasim
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This work was conducted (i) to measure the electrical conductance of dry and imbibing
seeda, (ii) to monitor the per cent age germination and spread of germination
of these species at varying temperature conditions and (iii) to find the optimal
germination conditions so that some biochemical and biomolecular studies could
be carried out in near future. Seeds of different plant species of Cholistan desert
such as Capparis decidua, Salvadora oleides and prosopis cineraria were allowed
to germinate at various temperature regimes and their per cent age germination
was monitored. Results show that optimal germination temperature for C. decidua
is 20°C (90% germination in 8 days), and for P. cineraria (65% in 10 days) and
S. oleiodes (85% in 4 days) is 30°C. Imbibition of P. cineraria in sand at 25°C
has been effective to get 80 per cent seeds germination. Electrical conductance
(μS/cm/10 seeds) measured during early hours/days of imbibition has been correlated
with the increase in fresh weight of imbibing seeds, through there is decrease
in the rate of electrolytes leakage ((μS/cm/hours/10 seeds) with increase in imbibitional
time. Work is in progress on the biochemical aspects of these early hours/days
of seed germination. |
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