Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the
coverage of the most important and influential journals
to meet the needs of the global scientific community.
The potential using of Acute Phase Proteins (APPs) in
the assessment of mammary gland health was studied by examining the levels
of Fibrinogen (Fb) and Ceruloplasmin (Cp) in plasma and milk from dairy
cows with different grades of mastitis. Plasma samples were taken from
jugular vein and milk samples were collected from quarters of cows with
subclinical and clinical mastitis, as well as healthy controls. California
Mastitis Test (CMT) were performed on each udder quarter of cows for detection
of CMT2+ and CMT3+ quarters. CMT (0) and culture negative cases were considered
healthy cows. Clinical mastitis, was graded as mild (clots in milk) or
moderate (clots in milk and visible signs of inflammation in the mammary
gland/s). The concentrations of Fb in the plasma of the cows with subclinical
and clinical mastitis were higher than in the plasma of the healthy cows
(p<0.01). There was no significant difference in plasma concentration
of Cp between healthy and subclinical groups (p>0.05), but differences
between clinical and healthy groups were significant (p<0.05). The
concentrations of Fb and Cp in the milk of the cows with subclinical and
clinical mastitis were higher than in the milk of the healthy cows (p<0.01).
The results indicated that measurement of Fb in plasma and milk and Cp
only in milk might be suitable for early diagnosis of mastitis in dairy
cows.
