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In this study, we proposed a framework for measuring knowledge transfer process in e-learning environment. This framework provides an element that covers all aspects to better evaluate the KTP and e-learning and provide a better description in explaining issues of effectiveness. We set up questionnaires to survey users of E-Faculty (e-learning system developed by FSKTM, UPM) and make a descriptive and inferential analysis for better findings on measurement attributes and correlation between hypothesis and testing result. We conclude that our framework provide a proper guideline to conduct evaluation on determining the effectiveness of process in e-learning.