Medicinal plants are viewed as a possible bridge between sustainable economic development, affordable health care and conservation of biodiversity. The present paper deals with the enumeration of 28 medicinally important plants frequently used by local communities of Phulpur tehsil of Allahabad district, Uttar Pradesh for the treatment of different ailments such as cold, cough, fever and gastro-intestinal disorders etc. The knowledge of local people about the indigenous plants used for medicinal purposes was collected through personal interview and group discussion during field trip. It was observed that 72% rural population of Phulpur tehsil were dependent on the indigenous medicinal plants (both wild and cultivated) for the treatment of various diseases and plant parts used most frequently were in the order: leaves>root>seeds>fruit>stem>whole plant> flower while approximately 28% local people expressed several reasons for not using the traditional medicines. It was also found that young people of new generation were not interested in the traditional medicines and according to their opinion the herbal treatment is not effective in comparison to modern system of medicine. This study provides immense scope for the bio-chemical analysis and screening of the active principles of the medicinal plants present in Phulpur tehsil for futuristic growth in the field of drug development.