This research was carried out to study the effect of two propagating methods on rooting ability and propagation of Tanasgol, a natural plum-apricot hybrid (Prunus domestica-armenia) developed in Shahrood, Iran. The propagation methods were hardwood cuttings and in vitro culture of seeds, set up as two separate experiments based on Completely Randomized Designs (CRD) with three replications and 20 cuttings/seeds for each replicate. Hardwood cuttings were treated in IBA-containing solutions of various concentrations (2000, 2500, 3000 and 4000 ppm). For in vitro culture, seeds were isolated from ripen fruits, surface sterilized and cultured on MS medium supplemented with 500 mg L-1 adenine sulfate, 1.5 g L-1 activated charcoal, 2 mg L-1 BAP and various concentrations of NAA (0.5, 1.0, 1.5, 2.0 mg L-1). After 60 days, the percentage of in vitrorooted seedlings was recorded. The results showed that the concentration of 3000 ppm IBA induced 47% rooting on hardwood cuttings and was better than other treatments significantly. The highest in vitroseed germination and rooting successfully (60%) was obtained on MS supplemented with 1.0 mg L-1 NAA. Therefore, more rooted plants (up to 1.3 times) would be obtained using in vitro culture techniques compared with hardwood cuttings.