Present study was undertaken to examine anti-inflammatory and analgesic activity
of ethanolic extract of Zizyphus nummularia (EAZN). EAZN produced anti-inflammatory
activity against acute paw oedema induced by carrageenan and histamine at the
dose levels of 200 and 300 mg kg-1, at the same dose levels EAZN
inhibited peritoneal leukocyte migration. Significant decrease in number of
writhes and increase in tail flick latency was observed in acetic acid induced
writhing and tail flick test, respectively. In conclusion, it is suggested that
inhibition of pain and inflammation mediators is the possible mechanism of action.