Abstract:
The ethanolic leaf extract of Eremomastax speciosa was evaluated for antimicrobial and antianaemic activities. The crude ethanolic extract, as well as n-hexane and acqueous fractions were tested against pure clinical cultures of Staphylococcus aureus, E. coli, Candida albicans and Aspergillus niger. The acqueous fraction showed a higher activity against all tested organisms except A.niger. This was followed by n-hexane fraction which showed a broad activity against all tested organisms. The crude extract was only active against E. coli and Staph. aureus. The ethanolic crude extract (500-2000 mg kg-1) also demonstrated antianaemic property by significantly (p< 0.01) elevating Red blood cell counts, packed cell volume, Haemoglobin concentration and white blood cell counts of rats treated with it. These findings justify the ethnomedical use of this plant.
J.E. Okokon, B.S. Antia, A.E. Udoh and M.M. Akpan, 2007. Antianaemic and Antimicrobial Activity of Eremomastax speciosa. Journal of Pharmacology and Toxicology, 2: 196-199.
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