The present study was initiated with a view to establish the possible effects of Hibiscus rosa sinensis on anxiety induced locomotor activity and exploratory behaviour in mice. Hibiscus rosa sinensis is an acclaimed important medicinal plant of Indian system of medicine recommended for its refrigerant and calming effect for centuries. In this study, the effect of alcoholic and chloroform extracts Hibiscus rosa sinensis on latency and exploratory behavior was studied by using open field test. The results obtained were analyzed by student t test. The results obtained in the open field test shows statistically significant decrease in exploratory behaviour, latency and increased rearing and ambulatory behaviour. Both the vertical and horizontal movements increased significantly as compared to the control group (p<0.05). Ethanolic extract showed better results than the chloroform extract (p<0.01). Both the extracts showed no significant increase in urination and defecation of the animals. The results suggest that Hibiscus rosa sinensis has significant anti-anxiety associated psychobehaviour modulation.
Khan Mohammed Junaid, Ajazuddin , Vyas Amber, Singh Manju and Singh Deependra, 2011. Acute and Chronic Effect of Hibiscus rosa sinensis Flower Extract on Anxiety Induced Exploratory and Locomotor Activity in Mice. Journal of Plant Sciences, 6: 102-107.