Present study has been performed to evaluate Extended Spectrum Beta-Lactamase (ESBL) positivity rates and antimicrobial susceptibility patterns for Escherichia coli and Klebsiella pneumoniae strains in order to make some regulations on antimicrobial policy in our medical institute. We retrospectively evaluated 297 strains (204 E. coli strains and 93 Klebsiella pneumoniae) isolated from inpatient clinics and internal care units of Canakkale State Hospital between November 2007-October 2008 performed by Clinical Microbiology Laboratory Unit. ESBL positivity was found 31.86% (65/204) of E. coli strains and 33.33% (31/93) of Klebsiella pneumoniae strains. Resistance of E. coli strains to amoxicillin clavulanate (AMC), ciprofloxacin (CIP) and trimethoprim-sulfamethoxazole (SXT) was found common (33.8, 33.8 and 36.8%, respectively) on the other hand K. pneumoniae strains more resistant to AMC (43%) but less resistant to CIP and SXT (22.6 and 31.2%). It is also found that hospitalization in intensive care units is a risk factor for elevated ESBL production rates.
F. Arabaci, M. Oldacay and D. Berber, 2009. Evaluation of ESBL Positivity Rates for Escherichia coli and Klebsiella pneumoniae Strains with the Sensititre ESBL Antimicrobic Susceptibility Plates in a Public Hospital, Turkey. Journal of Medical Sciences, 9: 103-107.