The aim of the present study was to record the sprains that occurred in students of the Athletic Facilitation Classes (AFC). The study was carried out at National Level from September 2006 to May 2007. During this period, 7455 male and 4921 female student-athletes were in close supervision of the researchers. The data were recorded by the physical education teachers of the AFC were registered in SPSS and they were analyzed with χ2 non-parametric test. During the study 248 sprains were recorded (21.9%, χ2 = 40.3, df = 17, p<0.05). One hundred and forty sprains (56.5%) occurred in the male and one hundred and eight (108) (43.5%) in female student-athletes (p<0.001). The rate of sprains was 1.88 per male per year and 2.52 per female student-athlete per year. Most sprains were recorded in the male than in female student-athletes that attended in AFC, which functioned in the capital of prefectures (68.1 vs. 31.9, χ2 = 12.0, df = 1, p<0.001). A significant number of sprains occurred during the months of November, December, January, February and March, while the sports in which most sprains occurred were basketball, volleyball and football. The training surface on which most sprains occurred was the parquet and the synthetic floor. It is concluded that the frequency of the sprains in the AFC is higher in males-athletes than in females occurred more in the sports of basketball, track and field, volley ball and soccer.