The present work was undertaken
to study the haematobiochemical changes in chlorpyriphos and T-2 toxin
fed broiler chicken. Known amounts of chlorpyriphos and T-2 toxin containing
powdered wheat substrates were incorporated into the toxin free broiler
starter mash, singly and in combination to yield 45 ppm chlorpyriphos
and 0.5 ppm T-2 toxin. Forty eight day-old broiler chicks were randomly
allotted into four groups of 12 each i.e., control, chlorpyriphos, T-2
and chlorpyriphos+T-2 groups and fed with toxin mixed diets from 0 to
4 weeks of age and studied various haematobiochemical parameters on
14th and 28th day of age. PCV and Hb levels decreased significantly
(P< 0.01) in toxin fed birds indicating anaemia. Serum total protein,
albumin, globulin and albumin/globulin ratio decreased significantly
(P< 0.01) in T-2 fed group. Serum glucose and cholesterol values decreased
significantly (P< 0.01) in chlorpyriphos group. AST, ALT and ALP values
increased significantly (P< 0.01) in T-2 and chlorpyriphos+T-2 groups.
Chlorpyriphos fed birds showed increased ALT. Chlorpyriphos and chlorpyriphos+T-2
fed groups showed significant (P< 0.01) increase in serum amylase values.
Decreased serum lipase values were observed in T-2 and chlorpyriphos+T-2
groups. No significant differences were observed in values of blood
urea nitrogen, creatinine, uric acid and GGT between the control and
toxin treated groups. Chlorpyriphos and T-2 toxins affected functions
of various organs in broiler chicken, the effect being less than additive.
P. Krishnamoorthy , S. Vairamuthu , C. Balachandran and B. Muralimanohar , 2006. Chlorpyriphos and T-2 Toxin Induced Haemato-Biochemical
Alterations in Broiler Chicken . International Journal of Poultry Science, 5: 173-177.