The purpose of this study was investigated that whether the measure of the
biochemical and urine parameters in pregnant women has correlation relationship
with preeclampsia. This study was targeted singleton pregnant women as the case
group (50 patients of preeclampsia) or the control group (50 healthy parturients)
who were admitted for termination of pregnancy due to medical or obstetrical
indications. In order to survey of serum iron, ferritin, creatinine, platelet
and liver enzymes, blood samples of case and control groups were taken before
delivery and analyzed. There was significant difference in the mean serum iron
and ferritin levels between two groups. Also, it was found significant differences
in the mean level of serum ferritin of the preeclamptic patients who have ELLP
syndrome (EL: Elevated liver enzyme, LP: Low platelet count) in comparison with
preeclampsia women with high level of liver enzymes. However, this relation
meaningful was not shown among mean serum iron and EELP syndrome with preeclampsia.
The correlation coefficients between iron and creatinine/proteinuria/albuminuria
as well as ferritin and creatinine/proteinuria/albuminuria concentrations in
group of preeclampsia were not significantly different. Present results revealed
that a correlation relationship between the concentration of serum ferritin
and iron and ELLP syndrome and preeclampsia may in fact exist.
Mahvash Zargar, Taghi Razi, Mahjobeh Ghanbarnejad and Masoud Hemadi, 2012. A Prospective Study of Evaluation of Changes in Biochemical and Urine Parameters in Pre-eclampsia. International Journal of Biological Chemistry, 6: 122-129.