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International Journal of Biological Chemistry
  Year: 2012 | Volume: 6 | Issue: 4 | Page No.: 122-129
DOI: 10.3923/ijbc.2012.122.129
A Prospective Study of Evaluation of Changes in Biochemical and Urine Parameters in Pre-eclampsia
Mahvash Zargar, Taghi Razi, Mahjobeh Ghanbarnejad and Masoud Hemadi

Abstract:
The purpose of this study was investigated that whether the measure of the biochemical and urine parameters in pregnant women has correlation relationship with preeclampsia. This study was targeted singleton pregnant women as the case group (50 patients of preeclampsia) or the control group (50 healthy parturients) who were admitted for termination of pregnancy due to medical or obstetrical indications. In order to survey of serum iron, ferritin, creatinine, platelet and liver enzymes, blood samples of case and control groups were taken before delivery and analyzed. There was significant difference in the mean serum iron and ferritin levels between two groups. Also, it was found significant differences in the mean level of serum ferritin of the preeclamptic patients who have ELLP syndrome (EL: Elevated liver enzyme, LP: Low platelet count) in comparison with preeclampsia women with high level of liver enzymes. However, this relation meaningful was not shown among mean serum iron and EELP syndrome with preeclampsia. The correlation coefficients between iron and creatinine/proteinuria/albuminuria as well as ferritin and creatinine/proteinuria/albuminuria concentrations in group of preeclampsia were not significantly different. Present results revealed that a correlation relationship between the concentration of serum ferritin and iron and ELLP syndrome and preeclampsia may in fact exist.
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How to cite this article:

Mahvash Zargar, Taghi Razi, Mahjobeh Ghanbarnejad and Masoud Hemadi, 2012. A Prospective Study of Evaluation of Changes in Biochemical and Urine Parameters in Pre-eclampsia. International Journal of Biological Chemistry, 6: 122-129.

DOI: 10.3923/ijbc.2012.122.129

URL: http://scialert.net/abstract/?doi=ijbc.2012.122.129

 
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