Abstract:
The effect of the administration of varying doses of FSH+LH (Pergonal®,
Ferring Labs, USA) was used on 16 clinically, sound, parous, West African
dwarf does aged 2-3 years to evaluate the hormonal profiles and superovulatory
responses. Four treatment groups were employed consisting of T1
(administered with physiological saline as the control), T2,
T3 and T4 given 19.0 IU, 58.0 IU and 82.0 IU FSH+LH,
respectively, as intramuscular injections over 3 days. The results on
the number of corpora lutea found on the ovary did not show any significant
difference (p>0.05) between goats on T2 (5.25±2.74)
T3 (6.25±2.13) and T4 (6.50±2.74).
However, they differed significantly (p<0.05) from goats on T1
(3.75±0.30) in the number of corpora lutea on the ovary. The number
of embryos recovered was not significantly different (p>0.05) between
goats on T2 (4.50±0.93), T3 (4.70±0.86)
and T4 (4.75±1.27). However, they differed significantly
(p<0.05) from goats on T1 (2.25±0.01) in number of
embryos recovered. Goats treated on T2 with embryo recovery
rate (78.30±0.18%) did not differ significantly (p>0.05) from
goats on T3 (75.20±0.14%) and T4 (73.10±0.06%).
However, they differed significantly (p<0.05) from goats on T1
(60.00±0.02%). The ova/embryo wastage was not significantly different
(p>0.05) between goats on T2 (21.70±0.30%), T3
(27.80±0.12%) and T4 (26.90±0.16%). However,
they differed significantly (p<0.05) from goats on T1 (40.00±0.01%)
in embryo wastage. LH and FSH were highest at T3 treatment
group with values of (3.60±0.02 and 3.13±0.14 (IU L-1),
respectively. Progesterone and Oestradiol showed higher values on T4
goats with (16.17±1.01 and 0.26±0.41 nmmol L-1),
respectively. The results of this study indicate that the administration
of FSH+LH enhanced embryo production and hormonal levels in West African
dwarf goats.
F.C. Iheukwumere, A.H. Abu and I.C. Okoli, 2008. Effect of FSH+LH (Pergonal®) Treatments on Hormonal
Profile and Superovulatory Response of West African Dwarf Does. Asian Journal of Scientific Research, 1: 281-287.
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