Subscribe Now Subscribe Today
 
FOLLOW US:     Facebook     Twitter
   
Asian Journal of Clinical Nutrition
  Year: 2014 | Volume: 6 | Issue: 2 | Page No.: 47-52
DOI: 10.3923/ajcn.2014.47.52
Berberis vulgaris Juice and Acne Vulgaris: A Placebo-Controlled Study
Mary Johnson and Naser Rafikhah

Abstract:
It has previously shown that aqueous extract of dried Berberis vulgaris fruit is useful against inflamed and total acne lesions. This study aimed to investigate the role of fresh Berberis vulgaris fruit juice in decreasing acne lesion counts in a group of patients with mild-to-moderate acne vulgaris. A total of 38 volunteers with mild-to moderate acne vulgaris were enrolled in this study; double-blind, placebo-controlled, randomized clinical trial. They received either 100 mL freshly prepared Berberis vulgaris fruit juice (n = 18, case group) or placebo (n = 20, control group) once daily for 30 consecutive days. Facial acne noninflamed, inflamed and total (noninflamed plus inflamed) lesions were counted at baseline, on week 2 and at endpoint (day 30) by an observer who was not aware of the grouping of patients. In the case group, there were 9 males (50%) and 9 females (50%) with a mean age of 16.1±3.9 years (Range: 12-25). In the control group, there were 9 males (45%) and 11 females (55%) with a mean age of 15.9±4.7 years (Range: 12-29). The two groups were matched for sex (p = 0.76) and age (p = 0.89). Changes in the mean count of noninflamed lesions were not different between the two groups (p = 0.33). In contrast, the mean number of inflamed and total acne lesions decreased significantly more pronounced in the case than in the control group (p = 0.01 and 0.02, respectively). In conclusion, this study showed that fresh Berberis vulgaris fruit juice is effective against acne lesions in patients with mild-to-moderate disease.
 [Fulltext PDF]   [Fulltext HTML]   [XML: Abstract + References]   [References]   [Report Citation]
 RELATED ARTICLES:
  •    Independent Predictors of In-hospital Re-bleeding, Need of Operation and Mortality in Acute Upper Gastrointestinal Bleeding
  •    Therapeutic Effects of Biguanide Vs. Statin in Polycystic Ovary Syndrome: A Randomized Clinical Trial
  •    Common Carotid Artery Intima-media Thickness and Atherosclerotic Plaques in Carotid Bulb in Patients with Chronic Kidney Disease on Hemodialysis: A Case-control Study
  •    Common Carotid Intima-media Thickness in Patients with Late Rheumatoid Arthritis; What Is the Role of Gender?
How to cite this article:

Mary Johnson and Naser Rafikhah, 2014. Berberis vulgaris Juice and Acne Vulgaris: A Placebo-Controlled Study. Asian Journal of Clinical Nutrition, 6: 47-52.

DOI: 10.3923/ajcn.2014.47.52

URL: http://scialert.net/abstract/?doi=ajcn.2014.47.52

 
COMMENT ON THIS PAPER
.