Subscribe Now Subscribe Today
Science Alert Home Journals at Science Alert For Authors For Subscribers Contact Us
   
Asian Journal of Biochemistry
  Year: 2007 | Volume: 2 | Issue: 2 | Page No.: 136-141
DOI: 10.3923/ajb.2007.136.141
Effects of Anthraquinone Glycosides and Aqueous Ethanol Extracts of Ficus sycomorus L. (Moraceae) on Rat Liver and Kidney Functions
S.W. Hassan, M. Lawal, B.Y. Muhammad, R.A. Umar, L.S. Bilbis and Y. Saidu

Abstract:
The anthraquinone glycosides composition and toxicity studies of isolated anthraquinone glycosides and aqueous ethanol stem bark extracts of Ficus sycomorus on rat liver and kidney functions were conducted. The yield of anthraquinone glycosides in 40 g powdered stem bark extract was 16.0% (w/v). Liver and renal indices were significantly (p<0.05) changed at higher doses of 617.86, 988.57 (anthraqiunone glycosides), 767.80 and 1228.60 mg kg-1 body weight (aqueous ethanol extract). Dose dependant decrease in weight (p<0.05) was observed in the rats administered higher doses of the aqueous ethanol and anthraquinone glycosides extracts. The results suggest that extracts of Ficus sycomorus cause adverse effects to liver and kidney at higher doses.
 [Fulltext PDF]   [Fulltext HTML]   [XML: Abstract + References]   [References]   [View Citation]  [Report Citation]
How to cite this article:

S.W. Hassan, M. Lawal, B.Y. Muhammad, R.A. Umar, L.S. Bilbis and Y. Saidu, 2007. Effects of Anthraquinone Glycosides and Aqueous Ethanol Extracts of Ficus sycomorus L. (Moraceae) on Rat Liver and Kidney Functions . Asian Journal of Biochemistry, 2: 136-141.

DOI: 10.3923/ajb.2007.136.141

URL: http://scialert.net/abstract/?doi=ajb.2007.136.141

 
COMMENT ON THIS PAPER
.
 
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 
 
 
 
 

                 home       |       journals        |       for authors       |       for subscribers       |       asci
          © Science Alert. All Rights Reserved